Cargando…

Design and In Vitro Study of a Dual Drug-Loaded Delivery System Produced by Electrospinning for the Treatment of Acute Injuries of the Central Nervous System

Vascular and traumatic injuries of the central nervous system are recognized as global health priorities. A polypharmacology approach that is able to simultaneously target several injury factors by the combination of agents having synergistic effects appears to be promising. Herein, we designed a po...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dolci, Luisa Stella, Perone, Rosaria Carmela, Di Gesù, Roberto, Kurakula, Mallesh, Gualandi, Chiara, Zironi, Elisa, Gazzotti, Teresa, Tondo, Maria Teresa, Pagliuca, Giampiero, Gostynska, Natalia, Baldassarro, Vito Antonio, Cescatti, Maura, Giardino, Luciana, Focarete, Maria Letizia, Calzà, Laura, Passerini, Nadia, Bolognesi, Maria Laura
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227370/ https://www.ncbi.nlm.nih.gov/pubmed/34201089 http://dx.doi.org/10.3390/pharmaceutics13060848

Ejemplares similares

In Vitro Testing of Biomaterials for Neural Repair: Focus on Cellular Systems and High-Content Analysis
por: Baldassarro, Vito Antonio, et al.
Publicado: (2016)

Preliminary monitoring of the presence of perfluoroalkyl substances in Italian eggs from different breeding systems
por: Ghelli, Elisa, et al.
Publicado: (2019)

Nerve growth factor promotes differentiation and protects the oligodendrocyte precursor cells from in vitro hypoxia/ischemia
por: Baldassarro, Vito Antonio, et al.
Publicado: (2023)

Analysis of Cobalamin (Vit B12) in Ripened Cheese by Ultra-High-Performance Liquid Chromatography Coupled with Mass Spectrometry
por: Rampazzo, Giulia, et al.
Publicado: (2022)

Glyphosate and Glufosinate Residues in Honey and Other Hive Products
por: Rampazzo, Giulia, et al.
Publicado: (2023)

Bisphenol A in Edible Part of Seafood
por: Repossi, Adele, et al.
Publicado: (2016)

Vitamin B12 determination in milk, whey and different by-products of ricotta cheese production by ultra performance liquid chromatography coupled with tandem mass spectrometry
por: Repossi, Adele, et al.
Publicado: (2017)

Occurrence of Mycotoxins in Extruded Commercial Cat Food
por: Grandi, Monica, et al.
Publicado: (2019)

Time-Course Changes of Extracellular Matrix Encoding Genes Expression Level in the Spinal Cord Following Contusion Injury—A Data-Driven Approach
por: Bighinati, Andrea, et al.
Publicado: (2021)

Nerve Growth Factor Biodelivery: A Limiting Step in Moving Toward Extensive Clinical Application?
por: Alastra, Giuseppe, et al.
Publicado: (2021)

Oligodendrocytes in a dish for the drug discovery pipeline: the risk of oversimplification
por: Baldassarro, Vito Antonio, et al.
Publicado: (2020)

Determination of Vitamin B(12) in Dairy Products by Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry
por: Zironi, Elisa, et al.
Publicado: (2014)

An LC–MS/MS method for the determination of budesonide and 16α-hydroxyprednisolone in dog plasma
por: Gazzotti, Teresa, et al.
Publicado: (2016)

Vulnerability of primary neurons derived from Tg2576 Alzheimer mice to oxygen and glucose deprivation: role of intraneuronal amyloid-β accumulation and astrocytes
por: Baldassarro, Vito Antonio, et al.
Publicado: (2017)

Molecular mechanisms of skin wound healing in non-diabetic and diabetic mice in excision and pressure experimental wounds
por: Baldassarro, Vito Antonio, et al.
Publicado: (2022)

Poly(l-lactic acid) Scaffold Releasing an α(4)β(1) Integrin Agonist Promotes Nonfibrotic Skin Wound Healing in Diabetic Mice
por: Baldassarro, Vito Antonio, et al.
Publicado: (2022)

Assessment of Perfluorooctane Sulfonate and Perfluorooctanoic Acid Exposure Through Fish Consumption in Italy
por: Barbarossa, Andrea, et al.
Publicado: (2016)

Enhanced Electrospinning of Active Organic Fibers by Plasma Treatment on Conjugated Polymer Solutions
por: Fasano, Vito, et al.
Publicado: (2020)

Neuroprotection and neuroregeneration: roles for the white matter
por: Baldassarro, Vito Antonio, et al.
Publicado: (2022)

Photobiomodulation at Defined Wavelengths Regulates Mitochondrial Membrane Potential and Redox Balance in Skin Fibroblasts
por: Baldassarro, Vito Antonio, et al.
Publicado: (2023)

A Modular Composite Device of Poly(Ethylene Oxide)/Poly(Butylene Terephthalate) (PEOT/PBT) Nanofibers and Gelatin as a Dual Drug Delivery System for Local Therapy of Soft Tissue Tumors
por: Liguori, Anna, et al.
Publicado: (2022)

Intra-individual variability in the neuroprotective and promyelinating properties of conditioned culture medium obtained from human adipose mesenchymal stromal cells
por: Baldassarro, Vito Antonio, et al.
Publicado: (2023)

Editorial: Electrospinning of Bioinspired Materials and Structures for Bioengineering and Advanced Biomedical Applications
por: Cristofolini, Luca, et al.
Publicado: (2021)

Pharmaceutical assessment of polyvinylpyrrolidone (PVP): As excipient from conventional to controlled delivery systems with a spotlight on COVID-19 inhibition
por: Kurakula, Mallesh, et al.
Publicado: (2020)

In vitro exposure to very low-level laser modifies expression level of extracellular matrix protein RNAs and mitochondria dynamics in mouse embryonic fibroblasts
por: Giuliani, Alessandro, et al.
Publicado: (2015)

White Matter and Neuroprotection in Alzheimer’s Dementia
por: Lorenzini, Luca, et al.
Publicado: (2020)

Thyroid Hormone Signaling in Embryonic Stem Cells: Crosstalk with the Retinoic Acid Pathway
por: Fernández, Mercedes, et al.
Publicado: (2020)

A Novel Three-Dimensional Culture Device Favors a Myelinating Morphology of Neural Stem Cell-Derived Oligodendrocytes
por: Flagelli, Alessandra, et al.
Publicado: (2021)

Composite of Elastin-Based Matrix and Electrospun Poly(L-Lactic Acid) Fibers: A Potential Smart Drug Delivery System
por: Bandiera, Antonella, et al.
Publicado: (2018)

“Combo” Multi-Target Pharmacological Therapy and New Formulations to Reduce Inflammation and Improve Endogenous Remyelination in Traumatic Spinal Cord Injury
por: Moretti, Marzia, et al.
Publicado: (2023)

A Time-Course Study of the Expression Level of Synaptic Plasticity-Associated Genes in Un-Lesioned Spinal Cord and Brain Areas in a Rat Model of Spinal Cord Injury: A Bioinformatic Approach
por: Baldassarro, Vito Antonio, et al.
Publicado: (2021)

Study on NGF and VEGF during the Equine Perinatal Period—Part 1: Healthy Foals Born from Normal Pregnancy and Parturition
por: Ellero, Nicola, et al.
Publicado: (2022)

Study on NGF and VEGF during the Equine Perinatal Period—Part 2: Foals Affected by Neonatal Encephalopathy
por: Ellero, Nicola, et al.
Publicado: (2022)

A critical point in chiral chromatography–mass spectrometry analysis of ketamine metabolites
por: Barbarossa, Andrea, et al.
Publicado: (2021)

Chitosan as Functional Biomaterial for Designing Delivery Systems in Cardiac Therapies
por: Patel, Bhaumik, et al.
Publicado: (2021)

Electrospinning of Fish Gelatin Solution Containing Citric Acid: An Environmentally Friendly Approach to Prepare Crosslinked Gelatin Fibers
por: Liguori, Anna, et al.
Publicado: (2019)

In Situ Gel Loaded with Chitosan-Coated Simvastatin Nanoparticles: Promising Delivery for Effective Anti-Proliferative Activity against Tongue Carcinoma
por: Kurakula, Mallesh, et al.
Publicado: (2020)

Dechlorane Plus and Related Compounds in Food—A Review
por: Ghelli, Elisa, et al.
Publicado: (2021)

Validation of a single liquid chromatography‐tandem mass spectrometry approach for oxytetracycline determination in bull plasma, seminal plasma and urine
por: Bardhi, Anisa, et al.
Publicado: (2022)

A single LC‐MS/MS validated method for tulathromycin quantification in plasma, seminal plasma, and urine to be applied in a pharmacokinetic study in bull
por: Barbarossa, Andrea, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_r76qgo5l1o42b516eldjepifi6