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Comparison of Resistance Spectra after First and Second Line Osimertinib Treatment Detected by Liquid Biopsy
SIMPLE SUMMARY: Since the recent approval of osimertinib, a third generation tyrosine kinase inhibitor (TKI) targeting EGFR in non-small cell lung cancer (NSCLC), tracing the resistance mechanisms that yield to failure of osimertinib has become of interest. As the spectrum of osimertinib-resistance...
Autores principales: | Jóri, Balázs, Schatz, Stefanie, Kaller, Len, Kah, Bettina, Roeper, Julia, Ramdani, Hayat O., Diehl, Linda, Hoffknecht, Petra, Grohé, Christian, Griesinger, Frank, Tiemann, Markus, Heukamp, Lukas C., Falk, Markus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227553/ https://www.ncbi.nlm.nih.gov/pubmed/34201252 http://dx.doi.org/10.3390/cancers13122861 |
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