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Modifiable Determinants of Postpartum Weight Loss in Women with Obesity: A Secondary Analysis of the UPBEAT Trial

Pregnancy can alter a woman’s weight gain trajectory across the life course and contribute to the development of obesity through retention of weight gained during pregnancy. This study aimed to identify modifiable determinants associated with postpartum weight retention (PPWR; calculated by the diff...

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Autores principales: Dalrymple, Kathryn V., Uwhubetine, Onome, Flynn, Angela C., Pasupathy, Dharmintra, Briley, Annette L., Relph, Sophie A., Seed, Paul T., O’Keeffe, Majella, Poston, Lucilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227672/
https://www.ncbi.nlm.nih.gov/pubmed/34207523
http://dx.doi.org/10.3390/nu13061979
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author Dalrymple, Kathryn V.
Uwhubetine, Onome
Flynn, Angela C.
Pasupathy, Dharmintra
Briley, Annette L.
Relph, Sophie A.
Seed, Paul T.
O’Keeffe, Majella
Poston, Lucilla
author_facet Dalrymple, Kathryn V.
Uwhubetine, Onome
Flynn, Angela C.
Pasupathy, Dharmintra
Briley, Annette L.
Relph, Sophie A.
Seed, Paul T.
O’Keeffe, Majella
Poston, Lucilla
author_sort Dalrymple, Kathryn V.
collection PubMed
description Pregnancy can alter a woman’s weight gain trajectory across the life course and contribute to the development of obesity through retention of weight gained during pregnancy. This study aimed to identify modifiable determinants associated with postpartum weight retention (PPWR; calculated by the difference in pre-pregnancy and 6 month postpartum weight) in 667 women with obesity from the UPBEAT study. We examined the relationship between PPWR and reported glycaemic load, energy intake, and smoking status in pregnancy, excessive gestational weight gain (GWG), mode of delivery, self-reported postpartum physical activity (low, moderate, and high), and mode of infant feeding (breast, formula, and mixed). At the 6 month visit, 48% (n = 320) of women were at or above pre-pregnancy weight. Overall, PPWR was negative (−0.06 kg (−42.0, 40.4)). Breastfeeding for ≥4 months, moderate or high levels of physical activity, and GWG ≤9 kg were associated with negative PPWR. These three determinants were combined to provide a modifiable factor score (range 0–3); for each added variable, a further reduction in PPWR of 3.0 kg (95% confidence interval 3.76, 2.25) occurred compared to women with no modifiable factors. This study identified three additive determinants of PPWR loss. These provide modifiable targets during pregnancy and the postnatal period to enable women with obesity to return to their pre-pregnancy weight.
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spelling pubmed-82276722021-06-26 Modifiable Determinants of Postpartum Weight Loss in Women with Obesity: A Secondary Analysis of the UPBEAT Trial Dalrymple, Kathryn V. Uwhubetine, Onome Flynn, Angela C. Pasupathy, Dharmintra Briley, Annette L. Relph, Sophie A. Seed, Paul T. O’Keeffe, Majella Poston, Lucilla Nutrients Article Pregnancy can alter a woman’s weight gain trajectory across the life course and contribute to the development of obesity through retention of weight gained during pregnancy. This study aimed to identify modifiable determinants associated with postpartum weight retention (PPWR; calculated by the difference in pre-pregnancy and 6 month postpartum weight) in 667 women with obesity from the UPBEAT study. We examined the relationship between PPWR and reported glycaemic load, energy intake, and smoking status in pregnancy, excessive gestational weight gain (GWG), mode of delivery, self-reported postpartum physical activity (low, moderate, and high), and mode of infant feeding (breast, formula, and mixed). At the 6 month visit, 48% (n = 320) of women were at or above pre-pregnancy weight. Overall, PPWR was negative (−0.06 kg (−42.0, 40.4)). Breastfeeding for ≥4 months, moderate or high levels of physical activity, and GWG ≤9 kg were associated with negative PPWR. These three determinants were combined to provide a modifiable factor score (range 0–3); for each added variable, a further reduction in PPWR of 3.0 kg (95% confidence interval 3.76, 2.25) occurred compared to women with no modifiable factors. This study identified three additive determinants of PPWR loss. These provide modifiable targets during pregnancy and the postnatal period to enable women with obesity to return to their pre-pregnancy weight. MDPI 2021-06-09 /pmc/articles/PMC8227672/ /pubmed/34207523 http://dx.doi.org/10.3390/nu13061979 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Dalrymple, Kathryn V.
Uwhubetine, Onome
Flynn, Angela C.
Pasupathy, Dharmintra
Briley, Annette L.
Relph, Sophie A.
Seed, Paul T.
O’Keeffe, Majella
Poston, Lucilla
Modifiable Determinants of Postpartum Weight Loss in Women with Obesity: A Secondary Analysis of the UPBEAT Trial
title Modifiable Determinants of Postpartum Weight Loss in Women with Obesity: A Secondary Analysis of the UPBEAT Trial
title_full Modifiable Determinants of Postpartum Weight Loss in Women with Obesity: A Secondary Analysis of the UPBEAT Trial
title_fullStr Modifiable Determinants of Postpartum Weight Loss in Women with Obesity: A Secondary Analysis of the UPBEAT Trial
title_full_unstemmed Modifiable Determinants of Postpartum Weight Loss in Women with Obesity: A Secondary Analysis of the UPBEAT Trial
title_short Modifiable Determinants of Postpartum Weight Loss in Women with Obesity: A Secondary Analysis of the UPBEAT Trial
title_sort modifiable determinants of postpartum weight loss in women with obesity: a secondary analysis of the upbeat trial
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227672/
https://www.ncbi.nlm.nih.gov/pubmed/34207523
http://dx.doi.org/10.3390/nu13061979
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