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Role of 1q21 in Multiple Myeloma: From Pathogenesis to Possible Therapeutic Targets
Multiple myeloma (MM) is characterized by an accumulation of malignant plasma cells (PCs) in the bone marrow (BM). The amplification of 1q21 is one of the most common cytogenetic abnormalities occurring in around 40% of de novo patients and 70% of relapsed/refractory MM. Patients with this unfavorab...
Autores principales: | Burroughs Garcìa, Jessica, Eufemiese, Rosa Alba, Storti, Paola, Sammarelli, Gabriella, Craviotto, Luisa, Todaro, Giannalisa, Toscani, Denise, Marchica, Valentina, Giuliani, Nicola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227721/ https://www.ncbi.nlm.nih.gov/pubmed/34205916 http://dx.doi.org/10.3390/cells10061360 |
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