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Feasibility of BRCA1/2 Testing of Formalin-Fixed and Paraffin-Embedded Pancreatic Tumor Samples: A Consecutive Clinical Series
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer, with most patients diagnosed at advanced stages. First-line treatment based on a combined chemotherapy (FOLFIRINOX or gemcitabine plus nab-paclitaxel) provides limited benefits. Olaparib, a PARP inhibitor, has been approved as maintena...
Autores principales: | Bruno, Rossella, Sensi, Elisa, Lupi, Cristiana, Giordano, Mirella, Bernardini, Laura, Vivaldi, Caterina, Fornaro, Lorenzo, Vasile, Enrico, Campani, Daniela, Fontanini, Gabriella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227758/ https://www.ncbi.nlm.nih.gov/pubmed/34200245 http://dx.doi.org/10.3390/diagnostics11061046 |
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