Cargando…
Structural and Biophysical Characterization of the HCV E1E2 Heterodimer for Vaccine Development
An effective vaccine for the hepatitis C virus (HCV) is a major unmet medical and public health need, and it requires an antigen that elicits immune responses to multiple key conserved epitopes. Decades of research have generated a number of vaccine candidates; based on these data and research throu...
Autores principales: | Toth, Eric A., Chagas, Andrezza, Pierce, Brian G., Fuerst, Thomas R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227786/ https://www.ncbi.nlm.nih.gov/pubmed/34072451 http://dx.doi.org/10.3390/v13061027 |
Ejemplares similares
-
A Biologically-validated HCV E1E2 Heterodimer Structural Model
por: Castelli, Matteo, et al.
Publicado: (2017) -
Induction of broadly neutralizing antibodies using a secreted form of the hepatitis C virus E1E2 heterodimer as a vaccine candidate
por: Wang, Ruixue, et al.
Publicado: (2022) -
Structure of engineered hepatitis C virus E1E2 ectodomain in complex with neutralizing antibodies
por: Metcalf, Matthew C., et al.
Publicado: (2023) -
Immunopotentiating and Delivery Systems for HCV Vaccines
por: Andrianov, Alexander K., et al.
Publicado: (2021) -
Functional expression and characterization of the envelope glycoprotein E1E2 heterodimer of hepatitis C virus
por: Cao, Longxing, et al.
Publicado: (2019)