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Loss of Selenov predisposes mice to extra fat accumulation and attenuated energy expenditure
Selenoprotein V (SELENOV) is a new and the least conserved member of the selenoprotein family. Herein we generated Selenov knockout (KO) mice to determine its in vivo function. The KO led to 16–19% increases (P < 0.05) in body weight that were largely due to 54% higher (P < 0.05) fat mass accu...
Autores principales: | Chen, Ling-Li, Huang, Jia-Qiang, Wu, Yuan-Yuan, Chen, Liang-Bing, Li, Shu-Ping, Zhang, Xu, Wu, Sen, Ren, Fa-Zheng, Lei, Xin-Gen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227834/ https://www.ncbi.nlm.nih.gov/pubmed/34167027 http://dx.doi.org/10.1016/j.redox.2021.102048 |
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