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The Role of the Key Effector of Necroptotic Cell Death, MLKL, in Mouse Models of Disease

Necroptosis is an inflammatory form of lytic programmed cell death that is thought to have evolved to defend against pathogens. Genetic deletion of the terminal effector protein—MLKL—shows no overt phenotype in the C57BL/6 mouse strain under conventional laboratory housing conditions. Small molecule...

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Detalles Bibliográficos
Autores principales:	Tovey Crutchfield, Emma C., Garnish, Sarah E., Hildebrand, Joanne M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227991/ https://www.ncbi.nlm.nih.gov/pubmed/34071602 http://dx.doi.org/10.3390/biom11060803

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