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Reducing Lung ATP Levels and Alleviating Asthmatic Airway Inflammation through Adeno-Associated Viral Vector-Mediated CD39 Expression

Asthma is a chronic respiratory inflammatory disease. Patients usually suffer long-term symptoms and high medical expenses. Extracellular ATP (eATP) has been identified as a danger signal in innate immunity and serves as a potent inflammatory mediator for asthma. Hydrolyzing eATP in lungs might be a...

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Detalles Bibliográficos
Autores principales: Huang, Yung-An, Chen, Jeng-Chang, Wu, Chih-Ching, Hsu, Chia-Wei, Ko, Albert Min-Shan, Chen, Li-Chen, Kuo, Ming-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228057/
https://www.ncbi.nlm.nih.gov/pubmed/34201190
http://dx.doi.org/10.3390/biomedicines9060656