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Blood Pressure Control and Antihypertensive Treatment among Hemodialysis Patients—Retrospective Single Center Experience

Background and Objectives: Hypertension affects at least 80% of hemodialysis patients. Inappropriate control of blood pressure is mentioned as one of the essential cardiovascular risk factors associated with development of cardiovascular events in dialysis populations. The aim of the cross-sectional...

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Autores principales: Skonieczny, Piotr, Heleniak, Zbigniew, Karowiec, Marek, Zajączkowski, Stanisław, Tylicki, Leszek, Dębska-Ślizień, Alicja, Rutkowski, Przemysław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228065/
https://www.ncbi.nlm.nih.gov/pubmed/34201168
http://dx.doi.org/10.3390/medicina57060590
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author Skonieczny, Piotr
Heleniak, Zbigniew
Karowiec, Marek
Zajączkowski, Stanisław
Tylicki, Leszek
Dębska-Ślizień, Alicja
Rutkowski, Przemysław
author_facet Skonieczny, Piotr
Heleniak, Zbigniew
Karowiec, Marek
Zajączkowski, Stanisław
Tylicki, Leszek
Dębska-Ślizień, Alicja
Rutkowski, Przemysław
author_sort Skonieczny, Piotr
collection PubMed
description Background and Objectives: Hypertension affects at least 80% of hemodialysis patients. Inappropriate control of blood pressure is mentioned as one of the essential cardiovascular risk factors associated with development of cardiovascular events in dialysis populations. The aim of the cross-sectional, retrospective study was the evaluation of the antihypertensive treatment schedule and control of blood pressure in relation to the guidelines in the group of hemodialysis patients. Additionally, we assessed the level of decrease in blood pressure by each group of hypotensive agents. Materials and Methods: 222 patients hemodialyzed in a single Dialysis Unit in three distinct periods of time—2006, 2011, and 2016—with a diagnosis of hypertension were enrolled in the study. The analysis of the antihypertensive treatment was based on the medical files and it consisted of a comparison of the mean blood pressure results reported during the six consecutive hemodialysis sessions. Results: The mean values of blood pressure before hemodialysis were as follows: 134/77, 130/74, and 140/76 mmHg, after hemodialysis 124/74, 126/73, and 139/77 mmHg in 2006, 2011, and 2016 respectively. The goal of predialysis blood pressure control (<140/90) was achieved by up to 64.3% of participants in 2006 as compared to 49.4% in 2016. Additionally, the postdialysis goal (<130/90) reached 57.1% of the study population in 2006 as compared to 27.1% of patients in 2016. The differences in percentage of patients using single, double, triple, and multidrug therapy during observation were not statistically significant. The most often used drugs were ß-blockers, diuretics, and calcium channel blockers in all points of the study. Blockades of the renin–angiotensin–aldosterone system in 2006 and calcium channel blockers in 2011 and 2016 were the drugs with highest impact on lowering blood pressure. Conclusions: The goal of predialysis or postdialysis blood pressure control was achieved in a lower percentage of patients during the period of the study. Blockade of renin–angiotensin–aldosterone system and calcium channel blockers decrease the blood pressure significantly. It is necessary to achieve better control of blood pressure in prevention of cardiovascular incidents.
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spelling pubmed-82280652021-06-26 Blood Pressure Control and Antihypertensive Treatment among Hemodialysis Patients—Retrospective Single Center Experience Skonieczny, Piotr Heleniak, Zbigniew Karowiec, Marek Zajączkowski, Stanisław Tylicki, Leszek Dębska-Ślizień, Alicja Rutkowski, Przemysław Medicina (Kaunas) Article Background and Objectives: Hypertension affects at least 80% of hemodialysis patients. Inappropriate control of blood pressure is mentioned as one of the essential cardiovascular risk factors associated with development of cardiovascular events in dialysis populations. The aim of the cross-sectional, retrospective study was the evaluation of the antihypertensive treatment schedule and control of blood pressure in relation to the guidelines in the group of hemodialysis patients. Additionally, we assessed the level of decrease in blood pressure by each group of hypotensive agents. Materials and Methods: 222 patients hemodialyzed in a single Dialysis Unit in three distinct periods of time—2006, 2011, and 2016—with a diagnosis of hypertension were enrolled in the study. The analysis of the antihypertensive treatment was based on the medical files and it consisted of a comparison of the mean blood pressure results reported during the six consecutive hemodialysis sessions. Results: The mean values of blood pressure before hemodialysis were as follows: 134/77, 130/74, and 140/76 mmHg, after hemodialysis 124/74, 126/73, and 139/77 mmHg in 2006, 2011, and 2016 respectively. The goal of predialysis blood pressure control (<140/90) was achieved by up to 64.3% of participants in 2006 as compared to 49.4% in 2016. Additionally, the postdialysis goal (<130/90) reached 57.1% of the study population in 2006 as compared to 27.1% of patients in 2016. The differences in percentage of patients using single, double, triple, and multidrug therapy during observation were not statistically significant. The most often used drugs were ß-blockers, diuretics, and calcium channel blockers in all points of the study. Blockades of the renin–angiotensin–aldosterone system in 2006 and calcium channel blockers in 2011 and 2016 were the drugs with highest impact on lowering blood pressure. Conclusions: The goal of predialysis or postdialysis blood pressure control was achieved in a lower percentage of patients during the period of the study. Blockade of renin–angiotensin–aldosterone system and calcium channel blockers decrease the blood pressure significantly. It is necessary to achieve better control of blood pressure in prevention of cardiovascular incidents. MDPI 2021-06-08 /pmc/articles/PMC8228065/ /pubmed/34201168 http://dx.doi.org/10.3390/medicina57060590 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Skonieczny, Piotr
Heleniak, Zbigniew
Karowiec, Marek
Zajączkowski, Stanisław
Tylicki, Leszek
Dębska-Ślizień, Alicja
Rutkowski, Przemysław
Blood Pressure Control and Antihypertensive Treatment among Hemodialysis Patients—Retrospective Single Center Experience
title Blood Pressure Control and Antihypertensive Treatment among Hemodialysis Patients—Retrospective Single Center Experience
title_full Blood Pressure Control and Antihypertensive Treatment among Hemodialysis Patients—Retrospective Single Center Experience
title_fullStr Blood Pressure Control and Antihypertensive Treatment among Hemodialysis Patients—Retrospective Single Center Experience
title_full_unstemmed Blood Pressure Control and Antihypertensive Treatment among Hemodialysis Patients—Retrospective Single Center Experience
title_short Blood Pressure Control and Antihypertensive Treatment among Hemodialysis Patients—Retrospective Single Center Experience
title_sort blood pressure control and antihypertensive treatment among hemodialysis patients—retrospective single center experience
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228065/
https://www.ncbi.nlm.nih.gov/pubmed/34201168
http://dx.doi.org/10.3390/medicina57060590
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