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Genomic Analysis of Avian Infectious Bronchitis Viruses Recently Isolated in South Korea Reveals Multiple Introductions of GI-19 Lineage (QX Genotype)

Infectious bronchitis virus (IBV) was first identified in the 1930s and it imposes a major economic burden on the poultry industry. In particular, GI-19 lineage has spread globally and has evolved constantly since it was first detected in China. In this study, we analyzed S1 gene sequences from 60 I...

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Autores principales: Lee, Hyuk-Chae, Jeong, Sol, Cho, Andrew Y., Kim, Kyu-Jik, Kim, Jun-Young, Park, Dam-Hee, Kim, Hyun-Jin, Kwon, Jung-Hoon, Song, Chang-Seon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228071/
https://www.ncbi.nlm.nih.gov/pubmed/34072981
http://dx.doi.org/10.3390/v13061045
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author Lee, Hyuk-Chae
Jeong, Sol
Cho, Andrew Y.
Kim, Kyu-Jik
Kim, Jun-Young
Park, Dam-Hee
Kim, Hyun-Jin
Kwon, Jung-Hoon
Song, Chang-Seon
author_facet Lee, Hyuk-Chae
Jeong, Sol
Cho, Andrew Y.
Kim, Kyu-Jik
Kim, Jun-Young
Park, Dam-Hee
Kim, Hyun-Jin
Kwon, Jung-Hoon
Song, Chang-Seon
author_sort Lee, Hyuk-Chae
collection PubMed
description Infectious bronchitis virus (IBV) was first identified in the 1930s and it imposes a major economic burden on the poultry industry. In particular, GI-19 lineage has spread globally and has evolved constantly since it was first detected in China. In this study, we analyzed S1 gene sequences from 60 IBVs isolated in South Korea. Two IBV lineages, GI-15 and GI-19, were identified in South Korea. Phylogenetic analysis suggested that there were six distinct subgroups (KM91-like, K40/09-like, and QX-like I to IV) of the South Korean GI-19 IBVs. Among them, QX-type III and IV subgroups, which are phylogenetically different from those reported in South Korea in the past, accounted for more than half of the total. Moreover, the phylogeographic analysis of the QX-like subgroups indicated at least four distinct introductions of GI-19 IBVs into South Korea during 2001–2020. The efficacy of commercialized vaccines against the recently introduced QX-like subgroups should be verified, and continuous international surveillance efforts and quarantine procedures should be enhanced to prevent the incursion of viruses.
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spelling pubmed-82280712021-06-26 Genomic Analysis of Avian Infectious Bronchitis Viruses Recently Isolated in South Korea Reveals Multiple Introductions of GI-19 Lineage (QX Genotype) Lee, Hyuk-Chae Jeong, Sol Cho, Andrew Y. Kim, Kyu-Jik Kim, Jun-Young Park, Dam-Hee Kim, Hyun-Jin Kwon, Jung-Hoon Song, Chang-Seon Viruses Article Infectious bronchitis virus (IBV) was first identified in the 1930s and it imposes a major economic burden on the poultry industry. In particular, GI-19 lineage has spread globally and has evolved constantly since it was first detected in China. In this study, we analyzed S1 gene sequences from 60 IBVs isolated in South Korea. Two IBV lineages, GI-15 and GI-19, were identified in South Korea. Phylogenetic analysis suggested that there were six distinct subgroups (KM91-like, K40/09-like, and QX-like I to IV) of the South Korean GI-19 IBVs. Among them, QX-type III and IV subgroups, which are phylogenetically different from those reported in South Korea in the past, accounted for more than half of the total. Moreover, the phylogeographic analysis of the QX-like subgroups indicated at least four distinct introductions of GI-19 IBVs into South Korea during 2001–2020. The efficacy of commercialized vaccines against the recently introduced QX-like subgroups should be verified, and continuous international surveillance efforts and quarantine procedures should be enhanced to prevent the incursion of viruses. MDPI 2021-05-31 /pmc/articles/PMC8228071/ /pubmed/34072981 http://dx.doi.org/10.3390/v13061045 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lee, Hyuk-Chae
Jeong, Sol
Cho, Andrew Y.
Kim, Kyu-Jik
Kim, Jun-Young
Park, Dam-Hee
Kim, Hyun-Jin
Kwon, Jung-Hoon
Song, Chang-Seon
Genomic Analysis of Avian Infectious Bronchitis Viruses Recently Isolated in South Korea Reveals Multiple Introductions of GI-19 Lineage (QX Genotype)
title Genomic Analysis of Avian Infectious Bronchitis Viruses Recently Isolated in South Korea Reveals Multiple Introductions of GI-19 Lineage (QX Genotype)
title_full Genomic Analysis of Avian Infectious Bronchitis Viruses Recently Isolated in South Korea Reveals Multiple Introductions of GI-19 Lineage (QX Genotype)
title_fullStr Genomic Analysis of Avian Infectious Bronchitis Viruses Recently Isolated in South Korea Reveals Multiple Introductions of GI-19 Lineage (QX Genotype)
title_full_unstemmed Genomic Analysis of Avian Infectious Bronchitis Viruses Recently Isolated in South Korea Reveals Multiple Introductions of GI-19 Lineage (QX Genotype)
title_short Genomic Analysis of Avian Infectious Bronchitis Viruses Recently Isolated in South Korea Reveals Multiple Introductions of GI-19 Lineage (QX Genotype)
title_sort genomic analysis of avian infectious bronchitis viruses recently isolated in south korea reveals multiple introductions of gi-19 lineage (qx genotype)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228071/
https://www.ncbi.nlm.nih.gov/pubmed/34072981
http://dx.doi.org/10.3390/v13061045
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