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Graphene Quantum Dots from Carbonized Coffee Bean Wastes for Biomedical Applications
Recent studies concerning graphene quantum dots (GQDs) focus extensively on their application in biomedicine, exploiting their modifiable optical properties and ability to complex with various molecules via π–π or covalent interactions. Among these nascent findings, the potential therapeutic efficac...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228242/ https://www.ncbi.nlm.nih.gov/pubmed/34071339 http://dx.doi.org/10.3390/nano11061423 |
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author | Kim, Dong Jin Yoo, Je Min Suh, Yeonjoon Kim, Donghoon Kang, Insung Moon, Joonhee Park, Mina Kim, Juhee Kang, Kyung-Sun Hong, Byung Hee |
author_facet | Kim, Dong Jin Yoo, Je Min Suh, Yeonjoon Kim, Donghoon Kang, Insung Moon, Joonhee Park, Mina Kim, Juhee Kang, Kyung-Sun Hong, Byung Hee |
author_sort | Kim, Dong Jin |
collection | PubMed |
description | Recent studies concerning graphene quantum dots (GQDs) focus extensively on their application in biomedicine, exploiting their modifiable optical properties and ability to complex with various molecules via π–π or covalent interactions. Among these nascent findings, the potential therapeutic efficacy of GQDs was reported against Parkinson’s disease, which has to date remained incurable. Herein, we present an environmentally friendly approach for synthesizing GQDs through a waste-to-treasure method, specifically from coffee waste to nanodrug. Consistent with the previous findings with carbon fiber-derived GQDs, the inhibitory effects of coffee bean-derived GQDs demonstrated similar effectiveness against abnormal α-synuclein fibrillation and the protection of neurons from relevant subcellular damages. The fact that a GQDs-based nanodrug can be prepared from a non-reusable yet edible source illustrates a potential approach to convert such waste materials into novel therapeutic agents with minimal psychological rejection by patients. |
format | Online Article Text |
id | pubmed-8228242 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-82282422021-06-26 Graphene Quantum Dots from Carbonized Coffee Bean Wastes for Biomedical Applications Kim, Dong Jin Yoo, Je Min Suh, Yeonjoon Kim, Donghoon Kang, Insung Moon, Joonhee Park, Mina Kim, Juhee Kang, Kyung-Sun Hong, Byung Hee Nanomaterials (Basel) Communication Recent studies concerning graphene quantum dots (GQDs) focus extensively on their application in biomedicine, exploiting their modifiable optical properties and ability to complex with various molecules via π–π or covalent interactions. Among these nascent findings, the potential therapeutic efficacy of GQDs was reported against Parkinson’s disease, which has to date remained incurable. Herein, we present an environmentally friendly approach for synthesizing GQDs through a waste-to-treasure method, specifically from coffee waste to nanodrug. Consistent with the previous findings with carbon fiber-derived GQDs, the inhibitory effects of coffee bean-derived GQDs demonstrated similar effectiveness against abnormal α-synuclein fibrillation and the protection of neurons from relevant subcellular damages. The fact that a GQDs-based nanodrug can be prepared from a non-reusable yet edible source illustrates a potential approach to convert such waste materials into novel therapeutic agents with minimal psychological rejection by patients. MDPI 2021-05-28 /pmc/articles/PMC8228242/ /pubmed/34071339 http://dx.doi.org/10.3390/nano11061423 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Communication Kim, Dong Jin Yoo, Je Min Suh, Yeonjoon Kim, Donghoon Kang, Insung Moon, Joonhee Park, Mina Kim, Juhee Kang, Kyung-Sun Hong, Byung Hee Graphene Quantum Dots from Carbonized Coffee Bean Wastes for Biomedical Applications |
title | Graphene Quantum Dots from Carbonized Coffee Bean Wastes for Biomedical Applications |
title_full | Graphene Quantum Dots from Carbonized Coffee Bean Wastes for Biomedical Applications |
title_fullStr | Graphene Quantum Dots from Carbonized Coffee Bean Wastes for Biomedical Applications |
title_full_unstemmed | Graphene Quantum Dots from Carbonized Coffee Bean Wastes for Biomedical Applications |
title_short | Graphene Quantum Dots from Carbonized Coffee Bean Wastes for Biomedical Applications |
title_sort | graphene quantum dots from carbonized coffee bean wastes for biomedical applications |
topic | Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228242/ https://www.ncbi.nlm.nih.gov/pubmed/34071339 http://dx.doi.org/10.3390/nano11061423 |
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