Cargando…
Synergistic Chromatin-Modifying Treatments Reactivate Latent HIV and Decrease Migration of Multiple Host-Cell Types
Upon infection of its host cell, human immunodeficiency virus (HIV) establishes a quiescent and non-productive state capable of spontaneous reactivation. Diverse cell types harboring the provirus form a latent reservoir, constituting a major obstacle to curing HIV. Here, we investigate the effects o...
Autores principales: | Blanco, Alexandra, Mahajan, Tarun, Coronado, Robert A., Ma, Kelly, Demma, Dominic R., Dar, Roy D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228244/ https://www.ncbi.nlm.nih.gov/pubmed/34201394 http://dx.doi.org/10.3390/v13061097 |
Ejemplares similares
-
Similarity in viral and host promoters couples viral reactivation with host cell migration
por: Bohn-Wippert, Kathrin, et al.
Publicado: (2017) -
KSHV Topologically Associating Domains in Latent and Reactivated Viral Chromatin
por: Campbell, Mel, et al.
Publicado: (2022) -
Chromatin control of Tat-mediated reactivation of latent HIV-1 provirus
por: Masse, Guillemette X, et al.
Publicado: (2009) -
The bromodomain and extraterminal domain inhibitor bromosporine synergistically reactivates latent HIV-1 in latently infected cells
por: Pan, Hanyu, et al.
Publicado: (2017) -
Internetwork connectivity of molecular networks across species of life
por: Mahajan, Tarun, et al.
Publicado: (2021)