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Activation of Anopheles stephensi Pantothenate Kinase and Coenzyme A Biosynthesis Reduces Infection with Diverse Plasmodium Species in the Mosquito Host
Malaria parasites require pantothenate from both human and mosquito hosts to synthesize coenzyme A (CoA). Specifically, mosquito-stage parasites cannot synthesize pantothenate de novo or take up preformed CoA from the mosquito host, making it essential for the parasite to obtain pantothenate from mo...
Autores principales: | Simão-Gurge, Raquel M., Thakre, Neha, Strickland, Jessica, Isoe, Jun, Delacruz, Lillian R., Torrevillas, Brandi K., Rodriguez, Anna M., Riehle, Michael A., Luckhart, Shirley |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228300/ https://www.ncbi.nlm.nih.gov/pubmed/34072373 http://dx.doi.org/10.3390/biom11060807 |
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