Effects of p-Cresol on Oxidative Stress, Glutathione Depletion, and Necrosis in HepaRG Cells: Comparisons to Other Uremic Toxins and the Role of p-Cresol Glucuronide Formation

The toxicological effects of p-cresol have primarily been attributed to its metabolism products; however, very little human data are available in the key organ (i.e., liver) responsible for the generation of these metabolites. Experiments were conducted in HepaRG cells utilizing the following marker...

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Detalles Bibliográficos
Autores principales: Zhu, Sang, Rong, Yan, Kiang, Tony K. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228354/
https://www.ncbi.nlm.nih.gov/pubmed/34207666
http://dx.doi.org/10.3390/pharmaceutics13060857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228354/
https://www.ncbi.nlm.nih.gov/pubmed/34207666
http://dx.doi.org/10.3390/pharmaceutics13060857

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