Survival Bias and Crosstalk between Chronological and Behavioral Age: Age- and Genotype-Sensitivity Tests Define Behavioral Signatures in Middle-Aged, Old, and Long-Lived Mice with Normal and AD-Associated Aging

New evidence refers to a high degree of heterogeneity in normal but also Alzheimer’s disease (AD) clinical and temporal patterns, increased mortality, and the need to find specific end-of-life prognosticators. This heterogeneity is scarcely explored in very old male AD mice models due to their reduc...

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Detalles Bibliográficos
Autores principales: Giménez-Llort, Lydia, Marin-Pardo, Daniela, Marazuela, Paula, Hernández-Guillamón, Mar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228433/
https://www.ncbi.nlm.nih.gov/pubmed/34199476
http://dx.doi.org/10.3390/biomedicines9060636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228433/
https://www.ncbi.nlm.nih.gov/pubmed/34199476
http://dx.doi.org/10.3390/biomedicines9060636

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