Temperate Bacteriophages—The Powerful Indirect Modulators of Eukaryotic Cells and Immune Functions

Bacteriophages are natural biological entities that limit the growth and amplification of bacteria. They are important stimulators of evolutionary variability in bacteria, and currently are considered a weapon against antibiotic resistance of bacteria. Nevertheless, apart from their antibacterial ac...

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Autores principales: Cieślik, Martyna, Bagińska, Natalia, Jończyk-Matysiak, Ewa, Węgrzyn, Alicja, Węgrzyn, Grzegorz, Górski, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228536/
https://www.ncbi.nlm.nih.gov/pubmed/34071422
http://dx.doi.org/10.3390/v13061013
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author Cieślik, Martyna
Bagińska, Natalia
Jończyk-Matysiak, Ewa
Węgrzyn, Alicja
Węgrzyn, Grzegorz
Górski, Andrzej
author_facet Cieślik, Martyna
Bagińska, Natalia
Jończyk-Matysiak, Ewa
Węgrzyn, Alicja
Węgrzyn, Grzegorz
Górski, Andrzej
author_sort Cieślik, Martyna
collection PubMed
description Bacteriophages are natural biological entities that limit the growth and amplification of bacteria. They are important stimulators of evolutionary variability in bacteria, and currently are considered a weapon against antibiotic resistance of bacteria. Nevertheless, apart from their antibacterial activity, phages may act as modulators of mammalian immune responses. In this paper, we focus on temperate phages able to execute the lysogenic development, which may shape animal or human immune response by influencing various processes, including phagocytosis of bacterial invaders and immune modulation of mammalian host cells.
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spelling pubmed-82285362021-06-26 Temperate Bacteriophages—The Powerful Indirect Modulators of Eukaryotic Cells and Immune Functions Cieślik, Martyna Bagińska, Natalia Jończyk-Matysiak, Ewa Węgrzyn, Alicja Węgrzyn, Grzegorz Górski, Andrzej Viruses Review Bacteriophages are natural biological entities that limit the growth and amplification of bacteria. They are important stimulators of evolutionary variability in bacteria, and currently are considered a weapon against antibiotic resistance of bacteria. Nevertheless, apart from their antibacterial activity, phages may act as modulators of mammalian immune responses. In this paper, we focus on temperate phages able to execute the lysogenic development, which may shape animal or human immune response by influencing various processes, including phagocytosis of bacterial invaders and immune modulation of mammalian host cells. MDPI 2021-05-28 /pmc/articles/PMC8228536/ /pubmed/34071422 http://dx.doi.org/10.3390/v13061013 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Cieślik, Martyna
Bagińska, Natalia
Jończyk-Matysiak, Ewa
Węgrzyn, Alicja
Węgrzyn, Grzegorz
Górski, Andrzej
Temperate Bacteriophages—The Powerful Indirect Modulators of Eukaryotic Cells and Immune Functions
title Temperate Bacteriophages—The Powerful Indirect Modulators of Eukaryotic Cells and Immune Functions
title_full Temperate Bacteriophages—The Powerful Indirect Modulators of Eukaryotic Cells and Immune Functions
title_fullStr Temperate Bacteriophages—The Powerful Indirect Modulators of Eukaryotic Cells and Immune Functions
title_full_unstemmed Temperate Bacteriophages—The Powerful Indirect Modulators of Eukaryotic Cells and Immune Functions
title_short Temperate Bacteriophages—The Powerful Indirect Modulators of Eukaryotic Cells and Immune Functions
title_sort temperate bacteriophages—the powerful indirect modulators of eukaryotic cells and immune functions
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228536/
https://www.ncbi.nlm.nih.gov/pubmed/34071422
http://dx.doi.org/10.3390/v13061013
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