Cargando…

Recognition Pattern of the Fasciola hepatica Excretome/Secretome during the Course of an Experimental Infection in Sheep by 2D Immunoproteomics

Excretory/secretory products released by helminth parasites have been widely studied for their diagnostic utility, immunomodulatory properties, as well as for their use as vaccines. Due to their location at the host/parasite interface, the characterization of parasite secretions is important to unra...

Descripción completa

Detalles Bibliográficos
Autores principales:	Becerro-Recio, David, González-Miguel, Javier, Ucero, Alberto, Sotillo, Javier, Martínez-Moreno, Álvaro, Pérez-Arévalo, José, Cwiklinski, Krystyna, Dalton, John P., Siles-Lucas, Mar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228785/ https://www.ncbi.nlm.nih.gov/pubmed/34207550 http://dx.doi.org/10.3390/pathogens10060725

Ejemplares similares

Study of the migration of Fasciola hepatica juveniles across the intestinal barrier of the host by quantitative proteomics in an ex vivo model
por: Becerro-Recio, David, et al.
Publicado: (2022)

Proteomics coupled with in vitro model to study the early crosstalk occurring between newly excysted juveniles of Fasciola hepatica and host intestinal cells
por: Becerro-Recio, David, et al.
Publicado: (2022)

Immune signatures of pathogenesis in the peritoneal compartment during early infection of sheep with Fasciola hepatica
por: Ruiz-Campillo, Maria Teresa, et al.
Publicado: (2017)

Exploiting Comparative Omics to Understand the Pathogenic and Virulence-Associated Protease: Anti-Protease Relationships in the Zoonotic Parasites Fasciola hepatica and Fasciola gigantica
por: Cwiklinski, Krystyna, et al.
Publicado: (2022)

Antigens from the Helminth Fasciola hepatica Exert Antiviral Effects against SARS-CoV-2 In Vitro
por: Serrat, Judit, et al.
Publicado: (2023)

Molecular Characterization of the Interplay between Fasciola hepatica Juveniles and Laminin as a Mechanism to Adhere to and Break through the Host Intestinal Wall
por: Serrat, Judit, et al.
Publicado: (2023)

Pathogenicity and virulence of the liver flukes Fasciola hepatica and Fasciola Gigantica that cause the zoonosis Fasciolosis
por: Lalor, Richard, et al.
Publicado: (2021)

Fasciola hepatica juveniles interact with the host fibrinolytic system as a potential early-stage invasion mechanism
por: Serrat, Judit, et al.
Publicado: (2023)

Fasciola hepatica vaccine: We may not be there yet but we’re on the right road
por: Molina-Hernández, Verónica, et al.
Publicado: (2015)

Antigen-specific response of CD4(+) T cells and hepatic lymph node cells to Fasciola hepatica-derived molecules at the early and late stage of the infection in sheep
por: Pérez-Caballero, Raúl, et al.
Publicado: (2021)

Fasciola hepatica Surface Tegument: Glycoproteins at the Interface of Parasite and Host
por: Ravidà, Alessandra, et al.
Publicado: (2016)

Complementary transcriptomic and proteomic analyses reveal the cellular and molecular processes that drive growth and development of Fasciola hepatica in the host liver
por: Cwiklinski, Krystyna, et al.
Publicado: (2021)

An atypical and functionally diverse family of Kunitz-type cysteine/serine proteinase inhibitors secreted by the helminth parasite Fasciola hepatica
por: Smith, David, et al.
Publicado: (2020)

Fasciola hepatica serine protease inhibitor family (serpins): Purposely crafted for regulating host proteases
por: De Marco Verissimo, Carolina, et al.
Publicado: (2020)

The Fasciola hepatica genome: gene duplication and polymorphism reveals adaptation to the host environment and the capacity for rapid evolution
por: Cwiklinski, Krystyna, et al.
Publicado: (2015)

Fasciola hepatica hijacks host macrophage miRNA machinery to modulate early innate immune responses
por: Tran, Nham, et al.
Publicado: (2021)

Tegument Glycoproteins and Cathepsins of Newly Excysted Juvenile Fasciola hepatica Carry Mannosidic and Paucimannosidic N-glycans
por: Garcia-Campos, Andres, et al.
Publicado: (2016)

Autonomous Non Antioxidant Roles for Fasciola hepatica Secreted Thioredoxin-1 and Peroxiredoxin-1
por: Dorey, Amber, et al.
Publicado: (2021)

Efficacy of a multivalent vaccine against Fasciola hepatica infection in sheep
por: Zafra, Rafael, et al.
Publicado: (2021)

The Zoonotic Helminth Parasite Fasciola hepatica: Virulence-Associated Cathepsin B and Cathepsin L Cysteine Peptidases Secreted by Infective Newly Excysted Juveniles (NEJ)
por: Barbour, Tara, et al.
Publicado: (2021)

Expression of free radicals by peritoneal cells of sheep during the early stages of Fasciola hepatica infection
por: Pérez-Caballero, Raúl, et al.
Publicado: (2018)

Fasciola hepatica is refractory to complement killing by preventing attachment of mannose binding lectin (MBL) and inhibiting MBL-associated serine proteases (MASPs) with serpins
por: De Marco Verissimo, Carolina, et al.
Publicado: (2022)

Targeting Secreted Protease/Anti-Protease Balance as a Vaccine Strategy against the Helminth Fasciola hepatica
por: Cwiklinski, Krystyna, et al.
Publicado: (2022)

Stage-specific miRNAs regulate gene expression associated with growth, development and parasite-host interaction during the intra-mammalian migration of the zoonotic helminth parasite Fasciola hepatica
por: Ricafrente, Alison, et al.
Publicado: (2022)

Clonal amplification of Fasciola hepatica in Galba truncatula: within and between isolate variation of triclabendazole-susceptible and -resistant clones
por: Hodgkinson, Jane E., et al.
Publicado: (2018)

The Extracellular Vesicles of the Helminth Pathogen, Fasciola hepatica: Biogenesis Pathways and Cargo Molecules Involved in Parasite Pathogenesis
por: Cwiklinski, Krystyna, et al.
Publicado: (2015)

Surface molecules of extracellular vesicles secreted by the helminth pathogen Fasciola hepatica direct their internalisation by host cells
por: de la Torre-Escudero, Eduardo, et al.
Publicado: (2019)

A major locus confers triclabendazole resistance in Fasciola hepatica and shows dominant inheritance
por: Beesley, Nicola J., et al.
Publicado: (2023)

Infection by the Helminth Parasite Fasciola hepatica Requires Rapid Regulation of Metabolic, Virulence, and Invasive Factors to Adjust to Its Mammalian Host
por: Cwiklinski, Krystyna, et al.
Publicado: (2018)

Life Cycle Stage-resolved Proteomic Analysis of the Excretome/Secretome from Strongyloides ratti—Identification of Stage-specific Proteases
por: Soblik, Hanns, et al.
Publicado: (2011)

In silico analyses of protein glycosylating genes in the helminth Fasciola hepatica (liver fluke) predict protein-linked glycan simplicity and reveal temporally-dynamic expression profiles
por: McVeigh, Paul, et al.
Publicado: (2018)

Fasciola hepatica in UK horses
por: Howell, A. K., et al.
Publicado: (2019)

Molecular Characteristics and Genetic Diversity of Fasciola Hepatica from Sheep in Xinjiang, China
por: Xifeng, Wang, et al.
Publicado: (2022)

Characterization of dendritic cells and follicular dendritic cells in the hepatic lymph nodes and liver of sheep experimentally infected with Fasciola hepatica
por: Ruiz-Campillo, María Teresa, et al.
Publicado: (2020)

Characterisation of a novel panel of polymorphic microsatellite loci for the liver fluke, Fasciola hepatica, using a next generation sequencing approach()
por: Cwiklinski, Krystyna, et al.
Publicado: (2015)

Fasciola hepatica Extracellular Vesicles isolated from excretory-secretory products using a gravity flow method modulate dendritic cell phenotype and activity
por: Murphy, Anna, et al.
Publicado: (2020)

Fasciola hepatica-Derived Molecules as Regulators of the Host Immune Response
por: Ryan, Sinéad, et al.
Publicado: (2020)

Influence of Fasciola hepatica on Serum Biochemical Parameters and Vascular and Biliary System of Sheep Liver
por: Hodžić, A, et al.
Publicado: (2013)

Molecular Characterization of Fasciola hepatica in Sheep Based on DNA Sequences of Ribosomal ITS-1
por: Alsulami, Muslimah N, et al.
Publicado: (2023)

Serological diagnosis of fasciolosis (Fasciola hepatica) in humans, cattle, and sheep: a meta-analysis
por: Drescher, Guilherme, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_f34t4s7sahf3vvin0ei1ef0qt3