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Appropriate Antibiotic Use and Associated Factors in Vietnamese Outpatients

Background: Inappropriate antibiotic use among outpatients is recognized as the primary driver of antibiotic resistance. A proper understanding of appropriate antibiotic usage and associated factors helps to determine and limit inappropriateness. We aimed to identify the rate of appropriate use of a...

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Autores principales: Nguyen, Lam V., Pham, Lien T. T., Bui, Anh L., Vi, Mai T., Nguyen, Nguyet K., Le, Tam T., Pham, Suol T., Nguyen, Phuong M., Nguyen, Thao H., Taxis, Katja, Nguyen, Thang, Tran, Hung D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228789/
https://www.ncbi.nlm.nih.gov/pubmed/34201175
http://dx.doi.org/10.3390/healthcare9060693
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author Nguyen, Lam V.
Pham, Lien T. T.
Bui, Anh L.
Vi, Mai T.
Nguyen, Nguyet K.
Le, Tam T.
Pham, Suol T.
Nguyen, Phuong M.
Nguyen, Thao H.
Taxis, Katja
Nguyen, Thang
Tran, Hung D.
author_facet Nguyen, Lam V.
Pham, Lien T. T.
Bui, Anh L.
Vi, Mai T.
Nguyen, Nguyet K.
Le, Tam T.
Pham, Suol T.
Nguyen, Phuong M.
Nguyen, Thao H.
Taxis, Katja
Nguyen, Thang
Tran, Hung D.
author_sort Nguyen, Lam V.
collection PubMed
description Background: Inappropriate antibiotic use among outpatients is recognized as the primary driver of antibiotic resistance. A proper understanding of appropriate antibiotic usage and associated factors helps to determine and limit inappropriateness. We aimed to identify the rate of appropriate use of antibiotics and identify factors associated with the inappropriate prescriptions. Methods: We conducted a cross-sectional descriptive study in outpatient antibiotic use at a hospital in Can Tho City, Vietnam, from August 1, 2019, to January 31, 2020. Data were extracted from all outpatient prescriptions at the Medical Examination Department and analyzed by SPSS 18 and Chi-squared tests, with 95% confidence intervals. The rationale for antibiotic use was evaluated through antibiotic selection, dose, dosing frequency, dosing time, interactions between antibiotics and other drugs, and general appropriate usage. Results: A total of 420 prescriptions were 51.7% for females, 61.7% with health insurance, and 44.0% for patients with one comorbid condition. The general appropriate antibiotic usage rate was 86.7%. Prescriptions showed that 11.0% and 9.5% had a higher dosing frequency and dose than recommended, respectively; 10.2% had an inappropriate dosing time; 3.1% had drug interactions; and only 1.7% had been prescribed inappropriate antibiotics. The risk of inappropriate antibiotic use increased in patients with comorbidities and antibiotic treatment lasting >7 days (p < 0.05). Conclusions: The study indicated a need for more consideration when prescribing antibiotics to patients with comorbidities or using more than 7 days of treatment.
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spelling pubmed-82287892021-06-26 Appropriate Antibiotic Use and Associated Factors in Vietnamese Outpatients Nguyen, Lam V. Pham, Lien T. T. Bui, Anh L. Vi, Mai T. Nguyen, Nguyet K. Le, Tam T. Pham, Suol T. Nguyen, Phuong M. Nguyen, Thao H. Taxis, Katja Nguyen, Thang Tran, Hung D. Healthcare (Basel) Article Background: Inappropriate antibiotic use among outpatients is recognized as the primary driver of antibiotic resistance. A proper understanding of appropriate antibiotic usage and associated factors helps to determine and limit inappropriateness. We aimed to identify the rate of appropriate use of antibiotics and identify factors associated with the inappropriate prescriptions. Methods: We conducted a cross-sectional descriptive study in outpatient antibiotic use at a hospital in Can Tho City, Vietnam, from August 1, 2019, to January 31, 2020. Data were extracted from all outpatient prescriptions at the Medical Examination Department and analyzed by SPSS 18 and Chi-squared tests, with 95% confidence intervals. The rationale for antibiotic use was evaluated through antibiotic selection, dose, dosing frequency, dosing time, interactions between antibiotics and other drugs, and general appropriate usage. Results: A total of 420 prescriptions were 51.7% for females, 61.7% with health insurance, and 44.0% for patients with one comorbid condition. The general appropriate antibiotic usage rate was 86.7%. Prescriptions showed that 11.0% and 9.5% had a higher dosing frequency and dose than recommended, respectively; 10.2% had an inappropriate dosing time; 3.1% had drug interactions; and only 1.7% had been prescribed inappropriate antibiotics. The risk of inappropriate antibiotic use increased in patients with comorbidities and antibiotic treatment lasting >7 days (p < 0.05). Conclusions: The study indicated a need for more consideration when prescribing antibiotics to patients with comorbidities or using more than 7 days of treatment. MDPI 2021-06-08 /pmc/articles/PMC8228789/ /pubmed/34201175 http://dx.doi.org/10.3390/healthcare9060693 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Nguyen, Lam V.
Pham, Lien T. T.
Bui, Anh L.
Vi, Mai T.
Nguyen, Nguyet K.
Le, Tam T.
Pham, Suol T.
Nguyen, Phuong M.
Nguyen, Thao H.
Taxis, Katja
Nguyen, Thang
Tran, Hung D.
Appropriate Antibiotic Use and Associated Factors in Vietnamese Outpatients
title Appropriate Antibiotic Use and Associated Factors in Vietnamese Outpatients
title_full Appropriate Antibiotic Use and Associated Factors in Vietnamese Outpatients
title_fullStr Appropriate Antibiotic Use and Associated Factors in Vietnamese Outpatients
title_full_unstemmed Appropriate Antibiotic Use and Associated Factors in Vietnamese Outpatients
title_short Appropriate Antibiotic Use and Associated Factors in Vietnamese Outpatients
title_sort appropriate antibiotic use and associated factors in vietnamese outpatients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228789/
https://www.ncbi.nlm.nih.gov/pubmed/34201175
http://dx.doi.org/10.3390/healthcare9060693
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