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Potential of Beetroot and Blackcurrant Compounds to Improve Metabolic Syndrome Risk Factors
Metabolic syndrome (MetS) is a group of metabolic abnormalities, which together lead to increased risk of coronary heart disease (CHD) and type 2 diabetes mellitus (T2DM), as well as reduced quality of life. Dietary nitrate, betalains and anthocyanins may improve risk factors for MetS and reduce the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228969/ https://www.ncbi.nlm.nih.gov/pubmed/34070362 http://dx.doi.org/10.3390/metabo11060338 |
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author | Haswell, Cameron Ali, Ajmol Page, Rachel Hurst, Roger Rutherfurd-Markwick, Kay |
author_facet | Haswell, Cameron Ali, Ajmol Page, Rachel Hurst, Roger Rutherfurd-Markwick, Kay |
author_sort | Haswell, Cameron |
collection | PubMed |
description | Metabolic syndrome (MetS) is a group of metabolic abnormalities, which together lead to increased risk of coronary heart disease (CHD) and type 2 diabetes mellitus (T2DM), as well as reduced quality of life. Dietary nitrate, betalains and anthocyanins may improve risk factors for MetS and reduce the risk of development of CHD and T2DM. Beetroot is a rich source of dietary nitrate, and anthocyanins are present in high concentrations in blackcurrants. This narrative review considers the efficacy of beetroot and blackcurrant compounds as potential agents to improve MetS risk factors, which could lead to decreased risk of CHD and T2DM. Further research is needed to establish the mechanisms through which these outcomes may occur, and chronic supplementation studies in humans may corroborate promising findings from animal models and acute human trials. |
format | Online Article Text |
id | pubmed-8228969 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-82289692021-06-26 Potential of Beetroot and Blackcurrant Compounds to Improve Metabolic Syndrome Risk Factors Haswell, Cameron Ali, Ajmol Page, Rachel Hurst, Roger Rutherfurd-Markwick, Kay Metabolites Review Metabolic syndrome (MetS) is a group of metabolic abnormalities, which together lead to increased risk of coronary heart disease (CHD) and type 2 diabetes mellitus (T2DM), as well as reduced quality of life. Dietary nitrate, betalains and anthocyanins may improve risk factors for MetS and reduce the risk of development of CHD and T2DM. Beetroot is a rich source of dietary nitrate, and anthocyanins are present in high concentrations in blackcurrants. This narrative review considers the efficacy of beetroot and blackcurrant compounds as potential agents to improve MetS risk factors, which could lead to decreased risk of CHD and T2DM. Further research is needed to establish the mechanisms through which these outcomes may occur, and chronic supplementation studies in humans may corroborate promising findings from animal models and acute human trials. MDPI 2021-05-25 /pmc/articles/PMC8228969/ /pubmed/34070362 http://dx.doi.org/10.3390/metabo11060338 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Haswell, Cameron Ali, Ajmol Page, Rachel Hurst, Roger Rutherfurd-Markwick, Kay Potential of Beetroot and Blackcurrant Compounds to Improve Metabolic Syndrome Risk Factors |
title | Potential of Beetroot and Blackcurrant Compounds to Improve Metabolic Syndrome Risk Factors |
title_full | Potential of Beetroot and Blackcurrant Compounds to Improve Metabolic Syndrome Risk Factors |
title_fullStr | Potential of Beetroot and Blackcurrant Compounds to Improve Metabolic Syndrome Risk Factors |
title_full_unstemmed | Potential of Beetroot and Blackcurrant Compounds to Improve Metabolic Syndrome Risk Factors |
title_short | Potential of Beetroot and Blackcurrant Compounds to Improve Metabolic Syndrome Risk Factors |
title_sort | potential of beetroot and blackcurrant compounds to improve metabolic syndrome risk factors |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228969/ https://www.ncbi.nlm.nih.gov/pubmed/34070362 http://dx.doi.org/10.3390/metabo11060338 |
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