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Potential of Beetroot and Blackcurrant Compounds to Improve Metabolic Syndrome Risk Factors

Metabolic syndrome (MetS) is a group of metabolic abnormalities, which together lead to increased risk of coronary heart disease (CHD) and type 2 diabetes mellitus (T2DM), as well as reduced quality of life. Dietary nitrate, betalains and anthocyanins may improve risk factors for MetS and reduce the...

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Autores principales: Haswell, Cameron, Ali, Ajmol, Page, Rachel, Hurst, Roger, Rutherfurd-Markwick, Kay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228969/
https://www.ncbi.nlm.nih.gov/pubmed/34070362
http://dx.doi.org/10.3390/metabo11060338
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author Haswell, Cameron
Ali, Ajmol
Page, Rachel
Hurst, Roger
Rutherfurd-Markwick, Kay
author_facet Haswell, Cameron
Ali, Ajmol
Page, Rachel
Hurst, Roger
Rutherfurd-Markwick, Kay
author_sort Haswell, Cameron
collection PubMed
description Metabolic syndrome (MetS) is a group of metabolic abnormalities, which together lead to increased risk of coronary heart disease (CHD) and type 2 diabetes mellitus (T2DM), as well as reduced quality of life. Dietary nitrate, betalains and anthocyanins may improve risk factors for MetS and reduce the risk of development of CHD and T2DM. Beetroot is a rich source of dietary nitrate, and anthocyanins are present in high concentrations in blackcurrants. This narrative review considers the efficacy of beetroot and blackcurrant compounds as potential agents to improve MetS risk factors, which could lead to decreased risk of CHD and T2DM. Further research is needed to establish the mechanisms through which these outcomes may occur, and chronic supplementation studies in humans may corroborate promising findings from animal models and acute human trials.
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spelling pubmed-82289692021-06-26 Potential of Beetroot and Blackcurrant Compounds to Improve Metabolic Syndrome Risk Factors Haswell, Cameron Ali, Ajmol Page, Rachel Hurst, Roger Rutherfurd-Markwick, Kay Metabolites Review Metabolic syndrome (MetS) is a group of metabolic abnormalities, which together lead to increased risk of coronary heart disease (CHD) and type 2 diabetes mellitus (T2DM), as well as reduced quality of life. Dietary nitrate, betalains and anthocyanins may improve risk factors for MetS and reduce the risk of development of CHD and T2DM. Beetroot is a rich source of dietary nitrate, and anthocyanins are present in high concentrations in blackcurrants. This narrative review considers the efficacy of beetroot and blackcurrant compounds as potential agents to improve MetS risk factors, which could lead to decreased risk of CHD and T2DM. Further research is needed to establish the mechanisms through which these outcomes may occur, and chronic supplementation studies in humans may corroborate promising findings from animal models and acute human trials. MDPI 2021-05-25 /pmc/articles/PMC8228969/ /pubmed/34070362 http://dx.doi.org/10.3390/metabo11060338 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Haswell, Cameron
Ali, Ajmol
Page, Rachel
Hurst, Roger
Rutherfurd-Markwick, Kay
Potential of Beetroot and Blackcurrant Compounds to Improve Metabolic Syndrome Risk Factors
title Potential of Beetroot and Blackcurrant Compounds to Improve Metabolic Syndrome Risk Factors
title_full Potential of Beetroot and Blackcurrant Compounds to Improve Metabolic Syndrome Risk Factors
title_fullStr Potential of Beetroot and Blackcurrant Compounds to Improve Metabolic Syndrome Risk Factors
title_full_unstemmed Potential of Beetroot and Blackcurrant Compounds to Improve Metabolic Syndrome Risk Factors
title_short Potential of Beetroot and Blackcurrant Compounds to Improve Metabolic Syndrome Risk Factors
title_sort potential of beetroot and blackcurrant compounds to improve metabolic syndrome risk factors
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228969/
https://www.ncbi.nlm.nih.gov/pubmed/34070362
http://dx.doi.org/10.3390/metabo11060338
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