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Genotoxicity and Gene Expression in the Rat Lung Tissue following Instillation and Inhalation of Different Variants of Amorphous Silica Nanomaterials (aSiO(2) NM)

Several reports on amorphous silica nanomaterial (aSiO(2) NM) toxicity have been questioning their safety. Herein, we investigated the in vivo pulmonary toxicity of four variants of aSiO(2) NM: SiO(2)_15_Unmod, SiO(2)_15_Amino, SiO(2)_7 and SiO(2)_40. We focused on alterations in lung DNA and protei...

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Detalles Bibliográficos
Autores principales:	Brandão, Fátima, Costa, Carla, Bessa, Maria João, Dumortier, Elise, Debacq-Chainiaux, Florence, Hubaux, Roland, Salmon, Michel, Laloy, Julie, Stan, Miruna S., Hermenean, Anca, Gharbia, Sami, Dinischiotu, Anca, Bannuscher, Anne, Hellack, Bryan, Haase, Andrea, Fraga, Sónia, Teixeira, João Paulo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228975/ https://www.ncbi.nlm.nih.gov/pubmed/34200147 http://dx.doi.org/10.3390/nano11061502

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