Cargando…
Cathepsin D—Managing the Delicate Balance
Lysosomal proteases play a crucial role in maintaining cell homeostasis. Human cathepsin D manages protein turnover degrading misfolded and aggregated proteins and favors apoptosis in the case of proteostasis disruption. However, when cathepsin D regulation is affected, it can contribute to numerous...
Autores principales: | Mijanovic, Olja, Petushkova, Anastasiia I., Brankovic, Ana, Turk, Boris, Solovieva, Anna B., Nikitkina, Angelina I., Bolevich, Sergey, Timashev, Peter S., Parodi, Alessandro, Zamyatnin, Andrey A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229105/ https://www.ncbi.nlm.nih.gov/pubmed/34198733 http://dx.doi.org/10.3390/pharmaceutics13060837 |
Ejemplares similares
-
Cathepsin K in Pathological Conditions and New Therapeutic and Diagnostic Perspectives
por: Mijanović, Olja, et al.
Publicado: (2022) -
Tissue Engineering Meets Nanotechnology: Molecular Mechanism Modulations in Cornea Regeneration
por: Mijanović, Olja, et al.
Publicado: (2021) -
Papain-Like Proteases as Coronaviral Drug Targets: Current Inhibitors, Opportunities, and Limitations
por: Petushkova, Anastasiia I., et al.
Publicado: (2020) -
Redox-Mediated Post-Translational Modifications of Proteolytic Enzymes and Their Role in Protease Functioning
por: Petushkova, Anastasiia I., et al.
Publicado: (2020) -
Structure determinants defining the specificity of papain-like cysteine proteases
por: Petushkova, Anastasiia I., et al.
Publicado: (2022)