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Local Colonic Administration of a Serine Protease Inhibitor Improves Post-Inflammatory Visceral Hypersensitivity in Rats
Dysregulation of the protease–antiprotease balance in the gastrointestinal tract has been suggested as a mechanism underlying visceral hypersensitivity in conditions such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). We aimed to study the potential therapeutic role of an in...
Autores principales: | Hanning, Nikita, De bruyn, Michelle, Ceuleers, Hannah, Boogaerts, Tim, Berg, Maya, Smet, Annemieke, De Schepper, Heiko U., Joossens, Jurgen, van Nuijs, Alexander L. N., De Man, Joris G., Augustyns, Koen, De Meester, Ingrid, De Winter, Benedicte Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229129/ https://www.ncbi.nlm.nih.gov/pubmed/34072320 http://dx.doi.org/10.3390/pharmaceutics13060811 |
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