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In Silico Prediction and Prioritization of Novel Selective Antimicrobial Drug Targets in Escherichia coli

Novel antimicrobials interfering with pathogen-specific targets can minimize the risk of perturbations of the gut microbiota (dysbiosis) during therapy. We employed an in silico approach to identify essential proteins in Escherichia coli that are either absent or have low sequence identity in seven...

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Detalles Bibliográficos
Autores principales: Svanberg Frisinger, Frida, Jana, Bimal, Donadio, Stefano, Guardabassi, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229198/
https://www.ncbi.nlm.nih.gov/pubmed/34070637
http://dx.doi.org/10.3390/antibiotics10060632