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In Silico Prediction and Prioritization of Novel Selective Antimicrobial Drug Targets in Escherichia coli
Novel antimicrobials interfering with pathogen-specific targets can minimize the risk of perturbations of the gut microbiota (dysbiosis) during therapy. We employed an in silico approach to identify essential proteins in Escherichia coli that are either absent or have low sequence identity in seven...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229198/ https://www.ncbi.nlm.nih.gov/pubmed/34070637 http://dx.doi.org/10.3390/antibiotics10060632 |