Cargando…

Successful Patient-Derived Organoid Culture of Gynecologic Cancers for Disease Modeling and Drug Sensitivity Testing

SIMPLE SUMMARY: In the conventional treatment of gynecologic malignancies, most patients receive similar ‘one-size-fits-all’ treatment. However, it is increasingly clear that standard therapies do not work in every patient, and it would be very helpful to have pretreatment predictive assays to provi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bi, Jianling, Newtson, Andreea M., Zhang, Yuping, Devor, Eric J., Samuelson, Megan I., Thiel, Kristina W., Leslie, Kimberly K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229222/ https://www.ncbi.nlm.nih.gov/pubmed/34200645 http://dx.doi.org/10.3390/cancers13122901

Ejemplares similares

Blocking autophagy overcomes resistance to dual histone deacetylase and proteasome inhibition in gynecologic cancer
por: Bi, Jianling, et al.
Publicado: (2022)

Advantages of Tyrosine Kinase Anti-Angiogenic Cediranib over Bevacizumab: Cell Cycle Abrogation and Synergy with Chemotherapy
por: Bi, Jianling, et al.
Publicado: (2021)

Molecular Characterization of Non-responders to Chemotherapy in Serous Ovarian Cancer
por: McDonald, Megan E., et al.
Publicado: (2019)

Creation and validation of models to predict response to primary treatment in serous ovarian cancer
por: Gonzalez Bosquet, Jesus, et al.
Publicado: (2021)

Bacterial, Archaea, and Viral Transcripts (BAVT) Expression in Gynecological Cancers and Correlation with Regulatory Regions of the Genome
por: Gonzalez-Bosquet, Jesus, et al.
Publicado: (2021)

Population Substructure Has Implications in Validating Next-Generation Cancer Genomics Studies with TCGA
por: Miller, Marina D., et al.
Publicado: (2019)

Identification of Novel Fusion Transcripts in High Grade Serous Ovarian Cancer
por: Newtson, Andreea, et al.
Publicado: (2021)

The Dawning of the Age of Personalized Medicine in Gynecologic Oncology
por: Leslie, Kimberly K., et al.
Publicado: (2020)

Microbial Communities in Gynecological Cancers and Their Association with Tumor Somatic Variation
por: Gonzalez-Bosquet, Jesus, et al.
Publicado: (2023)

A Prediction Model for Preoperative Risk Assessment in Endometrial Cancer Utilizing Clinical and Molecular Variables
por: Salinas, Erin A., et al.
Publicado: (2019)

Combination of Proteasome and Histone Deacetylase Inhibitors Overcomes the Impact of Gain-of-Function p53 Mutations
por: Meng, Xiangbing, et al.
Publicado: (2018)

Differential DNA methylation in high-grade serous ovarian cancer (HGSOC) is associated with tumor behavior
por: Reyes, Henry D., et al.
Publicado: (2019)

Integrated Clinical and Genomic Models to Predict Optimal Cytoreduction in High-Grade Serous Ovarian Cancer
por: Cardillo, Nicholas, et al.
Publicado: (2022)

AZD1775 Increases Sensitivity to Olaparib and Gemcitabine in Cancer Cells with p53 Mutations
por: Meng, Xiangbing, et al.
Publicado: (2018)

Oncomorphic TP53 Mutations in Gynecologic Cancers Lose the Normal Protein:Protein Interactions with the microRNA Microprocessing Complex
por: Brachova, Pavla, et al.
Publicado: (2014)

p53 mutation status is a primary determinant of placenta-specific protein 1 expression in serous ovarian cancers
por: Devor, Eric J., et al.
Publicado: (2017)

An integrated prediction model of recurrence in endometrial endometrioid cancers
por: Miller, Marina D, et al.
Publicado: (2019)

The Use of Endometrial Cancer Patient–Derived Organoid Culture for Drug Sensitivity Testing Is Feasible
por: Girda, Eugenia, et al.
Publicado: (2017)

Prediction of chemo-response in serous ovarian cancer
por: Gonzalez Bosquet, Jesus, et al.
Publicado: (2016)

Interval debulking surgery is not worth the wait: a National Cancer Database study comparing primary cytoreductive surgery versus neoadjuvant chemotherapy
por: Lyons, Yasmin A, et al.
Publicado: (2020)

Culture and differentiation of rabbit intestinal organoids and organoid-derived cell monolayers
por: Kardia, Egi, et al.
Publicado: (2021)

Identification of Novel lncRNAs in Ovarian Cancer and Their Impact on Overall Survival
por: Cardillo, Nicholas, et al.
Publicado: (2021)

Multiplexed live-cell imaging for drug responses in patient-derived organoid models of cancer
por: Colling, Kaitriana E., et al.
Publicado: (2023)

Organoids and Engineered Organ Systems
por: Samuelson, Linda C., et al.
Publicado: (2019)

Knockdown of MTDH Sensitizes Endometrial Cancer Cells to Cell Death Induction by Death Receptor Ligand TRAIL and HDAC Inhibitor LBH589 Co-Treatment
por: Meng, Xiangbing, et al.
Publicado: (2011)

miR-888: A Novel Cancer-Testis Antigen that Targets the Progesterone Receptor in Endometrial Cancer()()
por: Hovey, Adriann M., et al.
Publicado: (2015)

The Oncoplacental Gene Placenta-Specific Protein 1 Is Highly Expressed in Endometrial Tumors and Cell Lines
por: Devor, Eric J., et al.
Publicado: (2013)

hCG production by mucinous adenocarcinoma of the ovary in a reproductive aged woman
por: Wagner, Vincent, et al.
Publicado: (2018)

Engineered Matrices Enable the Culture of Human Patient‐Derived Intestinal Organoids
por: Hunt, Daniel R., et al.
Publicado: (2021)

Modeling Human Thyroid Development by Fetal Tissue‐Derived Organoid Culture
por: Liang, Jianqing, et al.
Publicado: (2022)

Preclinical testing of oncolytic adenovirus sensitivity in patient-derived tumor organoids
por: Pascual-Sabater, Silvia, et al.
Publicado: (2021)

Mathematical Models of Organoid Cultures
por: Montes-Olivas, Sandra, et al.
Publicado: (2019)

Advances in Organoid Culture Research
por: Xie, Zhiyuan, et al.
Publicado: (2022)

Liver organoid culture methods
por: Hu, Yiqing, et al.
Publicado: (2023)

microRNA expression patterns across seven cancers are highly correlated and dominated by evolutionarily ancient families
por: DEVOR, ERIC J., et al.
Publicado: (2014)

Suspended hydrogel culture as a method to scale up intestinal organoids
por: Co, Julia Y., et al.
Publicado: (2023)

Organoid Culture of Isolated Cells from Patient-derived Tissues with Colorectal Cancer
por: Xie, Bing-Ying, et al.
Publicado: (2016)

Isolation of Biopsy-Derived, Human Cervical Keratinocytes Propagated as Monolayer and Organoid Cultures
por: Villa, Peter L., et al.
Publicado: (2018)

Establishment of patient-derived three-dimensional organoid culture in renal cell carcinoma
por: Na, Joon Chae, et al.
Publicado: (2020)

Robust, Long-Term Culture of Endoderm-Derived Hepatic Organoids for Disease Modeling
por: Akbari, Soheil, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_kug164d888ai3vnlu37mv2os63