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Development of Physiologically Based Pharmacokinetic Model for Orally Administered Fexuprazan in Humans

Fexuprazan is a new drug candidate in the potassium-competitive acid blocker (P-CAB) family. As proton pump inhibitors (PPIs), P-CABs inhibit gastric acid secretion and can be used to treat gastric acid-related disorders such as gastroesophageal reflux disease (GERD). Physiologically based pharmacok...

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Detalles Bibliográficos
Autores principales:	Jeong, Yoo-Seong, Kim, Min-Soo, Lee, Nora, Lee, Areum, Chae, Yoon-Jee, Chung, Suk-Jae, Lee, Kyeong-Ryoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229463/ https://www.ncbi.nlm.nih.gov/pubmed/34072547 http://dx.doi.org/10.3390/pharmaceutics13060813

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