Repositioning Lopinavir, an HIV Protease Inhibitor, as a Promising Antifungal Drug: Lessons Learned from Candida albicans—In Silico, In Vitro and In Vivo Approaches

The repurposing strategy was applied herein to evaluate the effects of lopinavir, an aspartic protease inhibitor currently used in the treatment of HIV-infected individuals, on the globally widespread opportunistic human fungal pathogen Candida albicans by using in silico, in vitro and in vivo appro...

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Detalles Bibliográficos
Autores principales: Santos, André L. S., Braga-Silva, Lys A., Gonçalves, Diego S., Ramos, Lívia S., Oliveira, Simone S. C., Souza, Lucieri O. P., Oliveira, Vanessa S., Lins, Roberto D., Pinto, Marcia R., Muñoz, Julian E., Taborda, Carlos P., Branquinha, Marta H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229492/
https://www.ncbi.nlm.nih.gov/pubmed/34071195
http://dx.doi.org/10.3390/jof7060424

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