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A New Direction in Microfluidics: Printed Porous Materials

In this work, the feasibility of a novel direction for microfluidics is studied by demonstrating a set of new methods to fabricate microfluidic systems. Similarly to microfluidic paper-based analytical devices, porous materials are being used. However, alternative porous materials and different prin...

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Autores principales: Evard, Hanno, Priks, Hans, Saar, Indrek, Aavola, Heili, Tamm, Tarmo, Leito, Ivo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229541/
https://www.ncbi.nlm.nih.gov/pubmed/34201216
http://dx.doi.org/10.3390/mi12060671
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author Evard, Hanno
Priks, Hans
Saar, Indrek
Aavola, Heili
Tamm, Tarmo
Leito, Ivo
author_facet Evard, Hanno
Priks, Hans
Saar, Indrek
Aavola, Heili
Tamm, Tarmo
Leito, Ivo
author_sort Evard, Hanno
collection PubMed
description In this work, the feasibility of a novel direction for microfluidics is studied by demonstrating a set of new methods to fabricate microfluidic systems. Similarly to microfluidic paper-based analytical devices, porous materials are being used. However, alternative porous materials and different printing methods are used here to give the material the necessary pattern to act as a microfluidic system. In this work, microfluidic systems were produced by the following three separate methods: (1) by curing a porous monolithic polymer sheet into a necessary pattern with photolithography, (2) by screen printing silica gel particles with gypsum, and (3) by dispensing silica gel particles with polyvinyl acetate binder using a modified 3D printer. Different parameters of the printed chips were determined (strength of the printed material, printing accuracy, printed material height, wetting characteristics, repeatability) to evaluate whether the printed chips were suitable for use in microfluidics. All three approaches were found to be suitable, and therefore the novel approach to microfluidics was successfully demonstrated.
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spelling pubmed-82295412021-06-26 A New Direction in Microfluidics: Printed Porous Materials Evard, Hanno Priks, Hans Saar, Indrek Aavola, Heili Tamm, Tarmo Leito, Ivo Micromachines (Basel) Article In this work, the feasibility of a novel direction for microfluidics is studied by demonstrating a set of new methods to fabricate microfluidic systems. Similarly to microfluidic paper-based analytical devices, porous materials are being used. However, alternative porous materials and different printing methods are used here to give the material the necessary pattern to act as a microfluidic system. In this work, microfluidic systems were produced by the following three separate methods: (1) by curing a porous monolithic polymer sheet into a necessary pattern with photolithography, (2) by screen printing silica gel particles with gypsum, and (3) by dispensing silica gel particles with polyvinyl acetate binder using a modified 3D printer. Different parameters of the printed chips were determined (strength of the printed material, printing accuracy, printed material height, wetting characteristics, repeatability) to evaluate whether the printed chips were suitable for use in microfluidics. All three approaches were found to be suitable, and therefore the novel approach to microfluidics was successfully demonstrated. MDPI 2021-06-08 /pmc/articles/PMC8229541/ /pubmed/34201216 http://dx.doi.org/10.3390/mi12060671 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Evard, Hanno
Priks, Hans
Saar, Indrek
Aavola, Heili
Tamm, Tarmo
Leito, Ivo
A New Direction in Microfluidics: Printed Porous Materials
title A New Direction in Microfluidics: Printed Porous Materials
title_full A New Direction in Microfluidics: Printed Porous Materials
title_fullStr A New Direction in Microfluidics: Printed Porous Materials
title_full_unstemmed A New Direction in Microfluidics: Printed Porous Materials
title_short A New Direction in Microfluidics: Printed Porous Materials
title_sort new direction in microfluidics: printed porous materials
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229541/
https://www.ncbi.nlm.nih.gov/pubmed/34201216
http://dx.doi.org/10.3390/mi12060671
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