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Prevalence and Characteristics of Psoriasis in Romania—First Study in Overall Population

Background: Psoriasis is a chronic inflammatory disease characterized by an excessive hyperproliferation of keratinocytes and a combination of genetic, epigenetic, and environmental influences. The pathogenesis of psoriasis is complex and the exact mechanism remains elusive. Objectives: The study of...

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Autores principales: Nicolescu, Alin Codruț, Bucur, Ștefana, Giurcăneanu, Călin, Gheucă-Solovăstru, Laura, Constantin, Traian, Furtunescu, Florentina, Ancuța, Ioan, Constantin, Maria Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229555/
https://www.ncbi.nlm.nih.gov/pubmed/34200208
http://dx.doi.org/10.3390/jpm11060523
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author Nicolescu, Alin Codruț
Bucur, Ștefana
Giurcăneanu, Călin
Gheucă-Solovăstru, Laura
Constantin, Traian
Furtunescu, Florentina
Ancuța, Ioan
Constantin, Maria Magdalena
author_facet Nicolescu, Alin Codruț
Bucur, Ștefana
Giurcăneanu, Călin
Gheucă-Solovăstru, Laura
Constantin, Traian
Furtunescu, Florentina
Ancuța, Ioan
Constantin, Maria Magdalena
author_sort Nicolescu, Alin Codruț
collection PubMed
description Background: Psoriasis is a chronic inflammatory disease characterized by an excessive hyperproliferation of keratinocytes and a combination of genetic, epigenetic, and environmental influences. The pathogenesis of psoriasis is complex and the exact mechanism remains elusive. Objectives: The study of the prevalence of psoriasis will allow the estimation of the number of people suffering from this condition at the national level, as well as the development and validation of a questionnaire to estimate the prevalence and the risk factors associated with the disease. Methods: A quantitative research was conducted at a national level among the target population in order to validate the questionnaire and estimate the national prevalence. Results: Declaratively, the prevalence of psoriasis in the studied group (N = 1500) is 4%, the first symptoms appearing around the age of 50, with a certified diagnosis being made on average at 55 years. The prevalence of psoriasis vulgaris was 4.99%. Conclusions: The results obtained will be useful in guiding future initiatives and communication campaigns related to this condition, and the methodological approach used will provide the opportunity to make recommendations for improving similar initiatives in the future.
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spelling pubmed-82295552021-06-26 Prevalence and Characteristics of Psoriasis in Romania—First Study in Overall Population Nicolescu, Alin Codruț Bucur, Ștefana Giurcăneanu, Călin Gheucă-Solovăstru, Laura Constantin, Traian Furtunescu, Florentina Ancuța, Ioan Constantin, Maria Magdalena J Pers Med Article Background: Psoriasis is a chronic inflammatory disease characterized by an excessive hyperproliferation of keratinocytes and a combination of genetic, epigenetic, and environmental influences. The pathogenesis of psoriasis is complex and the exact mechanism remains elusive. Objectives: The study of the prevalence of psoriasis will allow the estimation of the number of people suffering from this condition at the national level, as well as the development and validation of a questionnaire to estimate the prevalence and the risk factors associated with the disease. Methods: A quantitative research was conducted at a national level among the target population in order to validate the questionnaire and estimate the national prevalence. Results: Declaratively, the prevalence of psoriasis in the studied group (N = 1500) is 4%, the first symptoms appearing around the age of 50, with a certified diagnosis being made on average at 55 years. The prevalence of psoriasis vulgaris was 4.99%. Conclusions: The results obtained will be useful in guiding future initiatives and communication campaigns related to this condition, and the methodological approach used will provide the opportunity to make recommendations for improving similar initiatives in the future. MDPI 2021-06-07 /pmc/articles/PMC8229555/ /pubmed/34200208 http://dx.doi.org/10.3390/jpm11060523 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Nicolescu, Alin Codruț
Bucur, Ștefana
Giurcăneanu, Călin
Gheucă-Solovăstru, Laura
Constantin, Traian
Furtunescu, Florentina
Ancuța, Ioan
Constantin, Maria Magdalena
Prevalence and Characteristics of Psoriasis in Romania—First Study in Overall Population
title Prevalence and Characteristics of Psoriasis in Romania—First Study in Overall Population
title_full Prevalence and Characteristics of Psoriasis in Romania—First Study in Overall Population
title_fullStr Prevalence and Characteristics of Psoriasis in Romania—First Study in Overall Population
title_full_unstemmed Prevalence and Characteristics of Psoriasis in Romania—First Study in Overall Population
title_short Prevalence and Characteristics of Psoriasis in Romania—First Study in Overall Population
title_sort prevalence and characteristics of psoriasis in romania—first study in overall population
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229555/
https://www.ncbi.nlm.nih.gov/pubmed/34200208
http://dx.doi.org/10.3390/jpm11060523
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