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DNA Methylation of Human Choline Kinase Alpha Promoter-Associated CpG Islands in MCF-7 Cells

Choline kinase (CK) is the enzyme catalyzing the first reaction in CDP-choline pathway for the biosynthesis of phosphatidylcholine. Higher expression of the α isozyme of CK has been implicated in carcinogenesis, and inhibition or downregulation of CKα (CHKA) is a promising anticancer approach. This...

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Detalles Bibliográficos
Autores principales:	Mohamed Sa’dom, Siti Aisyah Faten, Raikundalia, Sweta, Shamsuddin, Shaharum, See Too, Wei Cun, Few, Ling Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229565/ https://www.ncbi.nlm.nih.gov/pubmed/34205960 http://dx.doi.org/10.3390/genes12060853

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