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Erythropoietin Gene Therapy Delays Retinal Degeneration Resulting from Oxidative Stress in the Retinal Pigment Epithelium
Erythropoietin (EPO) plays an important role in erythropoiesis by its action in blocking apoptosis of progenitor cells and protects both photoreceptors and retinal ganglion cells from induced or inherited degeneration. A modified form of EPO, EPO-R76E has attenuated erythropoietic activity but is ef...
Autores principales: | Biswal, Manas R., Wang, Zhaoyao, Paulson, Ryan J., Uddin, Rukshana R., Tong, Yao, Zhu, Ping, Li, Hong, Lewin, Alfred S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229633/ https://www.ncbi.nlm.nih.gov/pubmed/34070383 http://dx.doi.org/10.3390/antiox10060842 |
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