A Virus-Like Particle-Based Vaccine Candidate against the Tick-Borne Powassan Virus Induces Neutralizing Antibodies in a Mouse Model

Powassan virus (POWV) is a tick-borne flavivirus circulating in North America and the Russian Far East that can cause severe neuroinvasive diseases, including encephalitis, meningitis, and meningoencephalitis. The reported neuroinvasive case fatality is about 10%, and approximately 50% of the surviv...

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Autores principales: Cimica, Velasco, Saleem, Sahar, Matuczinski, Emily, Adams-Fish, Debra, McMahon, Conor, Rashid, Sujatha, Stedman, Timothy T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229747/
https://www.ncbi.nlm.nih.gov/pubmed/34072726
http://dx.doi.org/10.3390/pathogens10060680

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