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Impact of Mixing on Content Uniformity of Thin Polymer Films Containing Drug Micro-Doses

The impact of mixer type and critical process parameters (CPPs) on critical quality attributes (CQAs), including the drug content uniformity (CU) of slurry-cast polymer films loaded with micro-sized poorly water-soluble drugs were investigated. Previously untested hypothesis was that the best mixer...

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Detalles Bibliográficos
Autores principales: Buyukgoz, Guluzar G., Castro, Jeremiah N., Atalla, Andrew E., Pentangelo, John G., Tripathi, Siddharth, Davé, Rajesh N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229899/
https://www.ncbi.nlm.nih.gov/pubmed/34072382
http://dx.doi.org/10.3390/pharmaceutics13060812