PARP Inhibitors Talazoparib and Niraparib Sensitize Melanoma Cells to Ionizing Radiation

(1) Background: Niraparib and Talazoparib are poly (ADP-ribose) polymerase (PARP) 1/2 inhibitors. It is assumed that combining PARP inhibitors with radiotherapy could be beneficial for cancer treatment. In this study, melanoma cells were treated with Niraparib and Talazoparib in combination with ion...

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Detalles Bibliográficos
Autores principales: Jonuscheit, Stephanie, Jost, Tina, Gajdošová, Fritzi, Wrobel, Maximilian, Hecht, Markus, Fietkau, Rainer, Distel, Luitpold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229922/
https://www.ncbi.nlm.nih.gov/pubmed/34073147
http://dx.doi.org/10.3390/genes12060849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229922/
https://www.ncbi.nlm.nih.gov/pubmed/34073147
http://dx.doi.org/10.3390/genes12060849

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