Sildenafil Counteracts the In Vitro Activation of CXCL-9, CXCL-10 and CXCL-11/CXCR3 Axis Induced by Reactive Oxygen Species in Scleroderma Fibroblasts

SIMPLE SUMMARY: Systemic sclerosis (SSc) is a complex autoimmune disease characterized by different clinical features and a high risk of mortality due to multi-organ fibrosis. Oxidative stress plays a key role in SSc pathogenesis, and an altered redox state could be responsible for abnormal inflamma...

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Detalles Bibliográficos
Autores principales: Antinozzi, Cristina, Sgrò, Paolo, Marampon, Francesco, Caporossi, Daniela, Del Galdo, Francesco, Dimauro, Ivan, Di Luigi, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229934/
https://www.ncbi.nlm.nih.gov/pubmed/34073032
http://dx.doi.org/10.3390/biology10060491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229934/
https://www.ncbi.nlm.nih.gov/pubmed/34073032
http://dx.doi.org/10.3390/biology10060491

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