Cargando…

Mori Ramulus Inhibits Pancreatic β-Cell Apoptosis and Prevents Insulin Resistance by Restoring Hepatic Mitochondrial Function

Type 2 diabetes mellitus is characterized by insulin resistance and pancreatic beta (β)-cell dysfunction. Accumulating evidence suggests that mitochondrial dysfunction may cause insulin resistance in peripheral tissues. As commercial hypoglycemic drugs have side effects, it is necessary to develop s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Taewon, Ko, Eun, Kim, Minji, Choi, Moonsung, Lee, Changho, Kim, In-Ho, Shin, Sooim, Um, Min Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229938/ https://www.ncbi.nlm.nih.gov/pubmed/34204891 http://dx.doi.org/10.3390/antiox10060901

Ejemplares similares

Antibacterial Effects of Ramulus mori Oligosaccharides against Streptococcus mutans
por: Li, Erna, et al.
Publicado: (2023)

Anti-inflammatory action of ethanolic extract of Ramulus mori on the BLT2-linked cascade
por: Park, Geun-Soo, et al.
Publicado: (2016)

Preparation of Polysaccharides from Ramulus mori, and Their Antioxidant, Anti-Inflammatory and Antibacterial Activities
por: Yu, Wansha, et al.
Publicado: (2019)

Mixed Exposure of Persistent Organic Pollutants Alters Oxidative Stress Markers and Mitochondrial Function in the Tail of Zebrafish Depending on Sex
por: Lee, Songhee, et al.
Publicado: (2021)

Ramulus Mori (Sangzhi) Alkaloids Ameliorate Obesity-Linked Adipose Tissue Metabolism and Inflammation in Mice
por: Sun, Qian-Wen, et al.
Publicado: (2022)

Anti-asthma and antitussive effects of a fermented extract of a mixture of Ramulus mori, Anthriscus sylvestris, and Salvia plebeian
por: An, Mirae, et al.
Publicado: (2021)

Lyophilized aqueous extracts of Mori Fructus and Mori Ramulus protect Mesenchymal stem cells from •OH–treated damage: bioassay and antioxidant mechanism
por: Jiang, Qian, et al.
Publicado: (2017)

Pharmacokinetics and tissue distribution of Ramulus Mori (Sangzhi) alkaloids in rats and its effects on liver enzyme activity
por: Liu, Zhihua, et al.
Publicado: (2023)

Mori Ramulus Suppresses Hydrogen Peroxide-Induced Oxidative Damage in Murine Myoblast C2C12 Cells through Activation of AMPK
por: Park, Cheol, et al.
Publicado: (2021)

Ramulus Mori (Sangzhi) Alkaloids Alleviate High-Fat Diet-Induced Obesity and Nonalcoholic Fatty Liver Disease in Mice
por: Chen, Yan-Min, et al.
Publicado: (2022)

Organization of the mitochondrial genome of Ramulus irregulatiter dentatus (Phasmatidae: Phasmatidae)
por: Zhang, Congfen, et al.
Publicado: (2022)

Ramulus mori (Sangzhi) alkaloids regulates gut microbiota disorder and its metabolism profiles in obese mice induced by a high-fat diet
por: Liu, Dongdong, et al.
Publicado: (2023)

Pharmacokinetics, Tissue Distribution, and Elimination of Three Active Alkaloids in Rats after Oral Administration of the Effective Fraction of Alkaloids from Ramulus Mori, an Innovative Hypoglycemic Agent
por: Yang, Shuang, et al.
Publicado: (2017)

Mori Ramulus (Chin.Ph.)—the Dried Twigs of Morus alba L./Part 1: Discovery of Two Novel Coumarin Glycosides from the Anti-Hyperuricemic Ethanol Extract
por: Yao, Jianbiao, et al.
Publicado: (2019)

Ramulus Mori (Sangzhi) Alkaloids (SZ-A) Ameliorate Glucose Metabolism Accompanied by the Modulation of Gut Microbiota and Ileal Inflammatory Damage in Type 2 Diabetic KKAy Mice
por: Liu, Quan, et al.
Publicado: (2021)

Tobacco etch virus (TEV) protease with multiple mutations to improve solubility and reduce self‐cleavage exhibits enhanced enzymatic activity
por: Nam, Heejin, et al.
Publicado: (2020)

Identification of Differential Compositions of Aqueous Extracts of Cinnamomi Ramulus and Cinnamomi Cortex
por: Wang, Pei, et al.
Publicado: (2023)

Integration of Transcriptomics and Lipidomics Profiling to Reveal the Therapeutic Mechanism Underlying Ramulus mori (Sangzhi) Alkaloids for the Treatment of Liver Lipid Metabolic Disturbance in High-Fat-Diet/Streptozotocin-Induced Diabetic Mice
por: Wang, Fan, et al.
Publicado: (2023)

Antifungal Activity of Ramulus cinnamomi Explored by (1)H-NMR Based Metabolomics Approach
por: Wan, Chunpeng, et al.
Publicado: (2017)

Bacteroides thetaiotaomicron Starch Utilization Promotes Quercetin Degradation and Butyrate Production by Eubacterium ramulus
por: Rodriguez-Castaño, Gina Paola, et al.
Publicado: (2019)

The Potentials of Uncariae Ramulus Cum Uncis for the Treatment of Migraine: Targeting CGRP in the Trigeminovascular System
por: Chong, Cheong-Meng, et al.
Publicado: (2021)

Cinnamomi ramulus inhibits cancer cells growth by inducing G2/M arrest
por: Li, Jing, et al.
Publicado: (2023)

Phylogeographical evidence for historical long-distance dispersal in the flightless stick insect Ramulus mikado
por: Suetsugu, Kenji, et al.
Publicado: (2023)

Randomized, Double-Blinded, Double-Dummy, Active-Controlled, and Multiple-Dose Clinical Study Comparing the Efficacy and Safety of Mulberry Twig (Ramulus Mori, Sangzhi) Alkaloid Tablet and Acarbose in Individuals with Type 2 Diabetes Mellitus
por: Li, Mengyi, et al.
Publicado: (2016)

The genomic underpinnings of apoptosis in the silkworm, Bombyx mori
por: Zhang, Jin-Ye, et al.
Publicado: (2010)

Treatment of Stress Urinary Incontinence by Cinnamaldehyde, the Major Constituent of the Chinese Medicinal Herb Ramulus Cinnamomi
por: Chen, Yung-Hsiang, et al.
Publicado: (2014)

Stability of Alkaloids during Drying Process and Their Effect on Anticoagulating Activity of Uncariae Ramulus Cum Uncis
por: Zou, Lu, et al.
Publicado: (2019)

Cinnamomi Ramulus inhibits the growth of colon cancer cells via Akt/ERK signaling pathways
por: Pan, Boyu, et al.
Publicado: (2022)

1,3-Dicaffeoylquinic Acid as an Active Compound of Arctium lappa Root Extract Ameliorates Depressive-Like Behavior by Regulating Hippocampal Nitric Oxide Synthesis in Ovariectomized Mice
por: Lim, Dong Wook, et al.
Publicado: (2021)

The complete mitochondrial genome of Yao silkworm (Bombyx mori)
por: Zhang, Gui-Zheng, et al.
Publicado: (2019)

Integrated Experimental Approach, Phytochemistry, and Network Pharmacology to Explore the Potential Mechanisms of Cinnamomi Ramulus for Rheumatoid Arthritis
por: Liu, Jia, et al.
Publicado: (2022)

Herba Gelsemii elegantis is detoxified by ramulus et folium Mussaendae pubescentis extract by modulating hepatic cytochrome P450 and glutathione S-transferase enzymes in rats
por: Wang, Yinghao, et al.
Publicado: (2018)

Combined Treatment of Mori folium and Mori Cortex Radicis Ameliorate Obesity in Mice via UCP-1 in Brown Adipocytes
por: Kim, Do-Sung, et al.
Publicado: (2023)

Multi-transgenic minipig models exhibiting potential for hepatic insulin resistance and pancreatic apoptosis
por: KONG, SIYUAN, et al.
Publicado: (2016)

Network Pharmacology-Based Analysis on the Mechanism of Action of Ephedrae Herba-Cinnamomi Ramulus Couplet Medicines in the Treatment for Psoriasis
por: Guo, Shun, et al.
Publicado: (2021)

Mori Folium and Mori Fructus Mixture Attenuates High-Fat Diet-Induced Cognitive Deficits in Mice
por: Kim, Hyo Geun, et al.
Publicado: (2015)

Complete mitochondrial genome of the highly fecund Bombyx mori linnaeus, 1758 (Lepidoptera: Bombycidae) strain Jam 146
por: Kim, Seong-Wan, et al.
Publicado: (2021)

Mechanisms underlying restoration of hepatic insulin sensitivity with CB1 antagonism in the obese dog model
por: Kim, Stella P.
Publicado: (2013)

Mechanism Study of Cinnamomi Ramulus and Paris polyphylla Sm. Drug Pair in the Treatment of Adenomyosis by Network Pharmacology and Experimental Validation
por: Zhang, Keke, et al.
Publicado: (2022)

Structural Basis for (2R,3R)-Taxifolin Binding and Reaction Products to the Bacterial Chalcone Isomerase of Eubacterium ramulus
por: Palm, Gottfried J., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_f46gti3vusd6gh7n2jsmsmv2vf