Antimicrobial Activity of Quasi-Enantiomeric Cinchona Alkaloid Derivatives and Prediction Model Developed by Machine Learning

Bacterial infections that do not respond to current treatments are increasing, thus there is a need for the development of new antibiotics. Series of 20 N-substituted quaternary salts of cinchonidine (CD) and their quasi-enantiomer cinchonine (CN) were prepared and their antimicrobial activity was a...

Descripción completa

Detalles Bibliográficos
Autores principales: Ramić, Alma, Skočibušić, Mirjana, Odžak, Renata, Čipak Gašparović, Ana, Milković, Lidija, Mikelić, Ana, Sović, Karlo, Primožič, Ines, Hrenar, Tomica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229948/
https://www.ncbi.nlm.nih.gov/pubmed/34073082
http://dx.doi.org/10.3390/antibiotics10060659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229948/
https://www.ncbi.nlm.nih.gov/pubmed/34073082
http://dx.doi.org/10.3390/antibiotics10060659

Ejemplares similares