Nontargeted Metabolomics by High-Resolution Mass Spectrometry to Study the In Vitro Metabolism of a Dual Inverse Agonist of Estrogen-Related Receptors β and γ, DN203368

DN203368 ((E)-3-[1-(4-[4-isopropylpiperazine-1-yl]phenyl) 3-methyl-2-phenylbut-1-en-1-yl] phenol) is a 4-hydroxy tamoxifen analog that is a dual inverse agonist of estrogen-related receptor β/γ (ERRβ/γ). ERRγ is an orphan nuclear receptor that plays an important role in development and homeostasis a...

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Detalles Bibliográficos
Autores principales: Kim, Sin-Eun, Ji, Seung-Bae, Kim, Euihyeon, Jeong, Minseon, Kim, Jina, Lee, Gyung-Min, Seo, Hyung-Ju, Bae, Subin, Jeong, Yeojin, Lee, Sangkyu, Kim, Sunghwan, Lee, Taeho, Cho, Sung Jin, Liu, Kwang-Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230175/
https://www.ncbi.nlm.nih.gov/pubmed/34072800
http://dx.doi.org/10.3390/pharmaceutics13060776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230175/
https://www.ncbi.nlm.nih.gov/pubmed/34072800
http://dx.doi.org/10.3390/pharmaceutics13060776

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