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A Rational Designed Novel Bispecific Antibody for the Treatment of GBM
Epidermal growth factor receptor variant III (EGFRvIII) is highly and specifically expressed in a subset of lethal glioblastoma (GBM), making the receptor a unique therapeutic target for GBM. Recently, bispecific antibodies (BsAbs) have shown exciting clinical benefits in cancer immunotherapy. Here,...
Autores principales: | Sun, Rui, Zhou, Yuexian, Han, Lei, Pan, Zhidi, Chen, Jie, Zong, Huifang, Bian, Yanlin, Jiang, Hua, Zhang, Baohong, Zhu, Jianwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230177/ https://www.ncbi.nlm.nih.gov/pubmed/34204931 http://dx.doi.org/10.3390/biomedicines9060640 |
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