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THAP9 Transposase Cleaves DNA via Conserved Acidic Residues in an RNaseH-Like Domain
The catalytic domain of most ‘cut and paste’ DNA transposases have the canonical RNase-H fold, which is also shared by other polynucleotidyl transferases such as the retroviral integrases and the RAG1 subunit of V(D)J recombinase. The RNase-H fold is a mixture of beta sheets and alpha helices with t...
Autores principales: | Sharma, Vasudha, Thakore, Prachi, Majumdar, Sharmistha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230255/ https://www.ncbi.nlm.nih.gov/pubmed/34072453 http://dx.doi.org/10.3390/cells10061351 |
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