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Coumarin-Based Triapine Derivatives and Their Copper(II) Complexes: Synthesis, Cytotoxicity and mR2 RNR Inhibition Activity
A series of thiosemicarbazone-coumarin hybrids (HL(1)-HL(3) and H(2)L(4)) has been synthesised in 12 steps and used for the preparation of mono- and dinuclear copper(II) complexes, namely Cu(HL(1))Cl(2) (1), Cu(HL(2))Cl(2) (2), Cu(HL(3))Cl(2) (3) and Cu(2)(H(2)L(4))Cl(4) (4), isolated in hydrated or...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230303/ https://www.ncbi.nlm.nih.gov/pubmed/34207929 http://dx.doi.org/10.3390/biom11060862 |