A Pan-Inhibitor for Protein Arginine Methyltransferase Family Enzymes

Protein arginine methyltransferases (PRMTs) play important roles in transcription, splicing, DNA damage repair, RNA biology, and cellular metabolism. Thus, PRMTs have been attractive targets for various diseases. In this study, we reported the design and synthesis of a potent pan-inhibitor for PRMTs...

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Detalles Bibliográficos
Autores principales: Iyamu, Iredia D., Al-Hamashi, Ayad A., Huang, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230315/
https://www.ncbi.nlm.nih.gov/pubmed/34201091
http://dx.doi.org/10.3390/biom11060854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230315/
https://www.ncbi.nlm.nih.gov/pubmed/34201091
http://dx.doi.org/10.3390/biom11060854

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