Intranasal Vaccine Delivery Technology for Respiratory Tract Disease Application with a Special Emphasis on Pneumococcal Disease

This mini-review will cover recent trends in intranasal (IN) vaccine delivery as it relates to applications for respiratory tract diseases. The logic and rationale for IN vaccine delivery will be compared to methods and applications accompanying this particular administration route. In addition, we...

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Detalles Bibliográficos
Autores principales: Walkowski, William, Bassett, Justin, Bhalla, Manmeet, Pfeifer, Blaine A., Ghanem, Elsa N. Bou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230341/
https://www.ncbi.nlm.nih.gov/pubmed/34199398
http://dx.doi.org/10.3390/vaccines9060589
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author Walkowski, William
Bassett, Justin
Bhalla, Manmeet
Pfeifer, Blaine A.
Ghanem, Elsa N. Bou
author_facet Walkowski, William
Bassett, Justin
Bhalla, Manmeet
Pfeifer, Blaine A.
Ghanem, Elsa N. Bou
author_sort Walkowski, William
collection PubMed
description This mini-review will cover recent trends in intranasal (IN) vaccine delivery as it relates to applications for respiratory tract diseases. The logic and rationale for IN vaccine delivery will be compared to methods and applications accompanying this particular administration route. In addition, we will focus extended discussion on the potential role of IN vaccination in the context of respiratory tract diseases, with a special emphasis on pneumococcal disease. Here, elements of this disease, including its prevalence and impact upon the elderly population, will be viewed from the standpoint of improving health outcomes through vaccine design and delivery technology and how IN administration can play a role in such efforts.
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spelling pubmed-82303412021-06-26 Intranasal Vaccine Delivery Technology for Respiratory Tract Disease Application with a Special Emphasis on Pneumococcal Disease Walkowski, William Bassett, Justin Bhalla, Manmeet Pfeifer, Blaine A. Ghanem, Elsa N. Bou Vaccines (Basel) Review This mini-review will cover recent trends in intranasal (IN) vaccine delivery as it relates to applications for respiratory tract diseases. The logic and rationale for IN vaccine delivery will be compared to methods and applications accompanying this particular administration route. In addition, we will focus extended discussion on the potential role of IN vaccination in the context of respiratory tract diseases, with a special emphasis on pneumococcal disease. Here, elements of this disease, including its prevalence and impact upon the elderly population, will be viewed from the standpoint of improving health outcomes through vaccine design and delivery technology and how IN administration can play a role in such efforts. MDPI 2021-06-02 /pmc/articles/PMC8230341/ /pubmed/34199398 http://dx.doi.org/10.3390/vaccines9060589 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Walkowski, William
Bassett, Justin
Bhalla, Manmeet
Pfeifer, Blaine A.
Ghanem, Elsa N. Bou
Intranasal Vaccine Delivery Technology for Respiratory Tract Disease Application with a Special Emphasis on Pneumococcal Disease
title Intranasal Vaccine Delivery Technology for Respiratory Tract Disease Application with a Special Emphasis on Pneumococcal Disease
title_full Intranasal Vaccine Delivery Technology for Respiratory Tract Disease Application with a Special Emphasis on Pneumococcal Disease
title_fullStr Intranasal Vaccine Delivery Technology for Respiratory Tract Disease Application with a Special Emphasis on Pneumococcal Disease
title_full_unstemmed Intranasal Vaccine Delivery Technology for Respiratory Tract Disease Application with a Special Emphasis on Pneumococcal Disease
title_short Intranasal Vaccine Delivery Technology for Respiratory Tract Disease Application with a Special Emphasis on Pneumococcal Disease
title_sort intranasal vaccine delivery technology for respiratory tract disease application with a special emphasis on pneumococcal disease
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230341/
https://www.ncbi.nlm.nih.gov/pubmed/34199398
http://dx.doi.org/10.3390/vaccines9060589
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