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Simulated Gastric Digestion and In Vivo Intestinal Uptake of Orally Administered CuO Nanoparticles and TiO(2) E171 in Male and Female Rat Pups

Oral exposure to nanoparticles (NPs) during early life is an understudied area. The goals of this study were to evaluate the effect of pre-weaned rat gastric fluids on 50 nm CuO NPs and TiO(2) E171 in vitro, and to evaluate uptake in vivo. The NP uptake was studied in vivo in male and female Sprague...

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Detalles Bibliográficos
Autores principales: Mortensen, Ninell P., Moreno Caffaro, Maria, Aravamudhan, Shyam, Beeravalli, Lakshmi, Prattipati, Sharmista, Snyder, Rodney W., Watson, Scott L., Patel, Purvi R., Weber, Frank X., Montgomery, Stephanie A., Sumner, Susan J., Fennell, Timothy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230348/
https://www.ncbi.nlm.nih.gov/pubmed/34199726
http://dx.doi.org/10.3390/nano11061487

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