Crystallography, Molecular Modeling, and COX-2 Inhibition Studies on Indolizine Derivatives

The cyclooxygenase-2 (COX-2) enzyme is an important target for drug discovery and development of novel anti-inflammatory agents. Selective COX-2 inhibitors have the advantage of reduced side-effects, which result from COX-1 inhibition that is usually observed with nonselective COX inhibitors. In thi...

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Detalles Bibliográficos
Autores principales: Venugopala, Katharigatta N., Chandrashekharappa, Sandeep, Tratrat, Christophe, Deb, Pran Kishore, Nagdeve, Rahul D., Nayak, Susanta K., Morsy, Mohamed A., Borah, Pobitra, Mahomoodally, Fawzi M., Mailavaram, Raghu Prasad, Attimarad, Mahesh, Aldhubiab, Bandar E., Sreeharsha, Nagaraja, Nair, Anroop B., Alwassil, Osama I., Haroun, Michelyne, Mohanlall, Viresh, Shinu, Pottathil, Venugopala, Rashmi, Kandeel, Mahmoud, Nandeshwarappa, Belakatte P., Ibrahim, Yasmine F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230391/
https://www.ncbi.nlm.nih.gov/pubmed/34200764
http://dx.doi.org/10.3390/molecules26123550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230391/
https://www.ncbi.nlm.nih.gov/pubmed/34200764
http://dx.doi.org/10.3390/molecules26123550

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