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Severe Pneumonia and Sepsis Caused by Dialister pneumosintes in an Adolescent
Background: Dialister pneumosintes (D. pneumosintes) is known to cause dental, periodontal or sinus infections. To date, the pathogen has only been described in a small number of cases with a severe infection. Case report: We describe the clinical case of a 13-year-old, obese female patient that pre...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230426/ https://www.ncbi.nlm.nih.gov/pubmed/34200808 http://dx.doi.org/10.3390/pathogens10060733 |
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author | Kaiser, Maximilian Weis, Meike Kehr, Katharina Varnholt, Verena Schroten, Horst Tenenbaum, Tobias |
author_facet | Kaiser, Maximilian Weis, Meike Kehr, Katharina Varnholt, Verena Schroten, Horst Tenenbaum, Tobias |
author_sort | Kaiser, Maximilian |
collection | PubMed |
description | Background: Dialister pneumosintes (D. pneumosintes) is known to cause dental, periodontal or sinus infections. To date, the pathogen has only been described in a small number of cases with a severe infection. Case report: We describe the clinical case of a 13-year-old, obese female patient that presented with acute respiratory failure and sepsis. A CT-scan showed extensive bilateral patchy areas, subpleural and peribronchovascular consolidations with surrounding ground-glass opacity, extensive consolidations in the lower lobes of both lungs matching to a severe pneumonia and clinically emerging acute respiratory distress syndrome. Moreover, it showed extensive sinusitis of the right sinus frontalis, maxillaris and right cellulae ethmoidales. D. pneumosintes was isolated from an anaerobic blood culture obtained at admission. The antibiotic treatment included piperacillin/tazobactam and oral switch to ampicillin/sulbactam plus ciprofloxacin. Conclusions: We describe the first adolescent with severe systemic D. pneumosintes infection. Since the pathogen is difficult to culture the systemic virulence remains unclear. This work aims to sensitize health care specialists to consider D. pneumosintes infection in patients with periodontal or sinusal infection. |
format | Online Article Text |
id | pubmed-8230426 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-82304262021-06-26 Severe Pneumonia and Sepsis Caused by Dialister pneumosintes in an Adolescent Kaiser, Maximilian Weis, Meike Kehr, Katharina Varnholt, Verena Schroten, Horst Tenenbaum, Tobias Pathogens Case Report Background: Dialister pneumosintes (D. pneumosintes) is known to cause dental, periodontal or sinus infections. To date, the pathogen has only been described in a small number of cases with a severe infection. Case report: We describe the clinical case of a 13-year-old, obese female patient that presented with acute respiratory failure and sepsis. A CT-scan showed extensive bilateral patchy areas, subpleural and peribronchovascular consolidations with surrounding ground-glass opacity, extensive consolidations in the lower lobes of both lungs matching to a severe pneumonia and clinically emerging acute respiratory distress syndrome. Moreover, it showed extensive sinusitis of the right sinus frontalis, maxillaris and right cellulae ethmoidales. D. pneumosintes was isolated from an anaerobic blood culture obtained at admission. The antibiotic treatment included piperacillin/tazobactam and oral switch to ampicillin/sulbactam plus ciprofloxacin. Conclusions: We describe the first adolescent with severe systemic D. pneumosintes infection. Since the pathogen is difficult to culture the systemic virulence remains unclear. This work aims to sensitize health care specialists to consider D. pneumosintes infection in patients with periodontal or sinusal infection. MDPI 2021-06-10 /pmc/articles/PMC8230426/ /pubmed/34200808 http://dx.doi.org/10.3390/pathogens10060733 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Kaiser, Maximilian Weis, Meike Kehr, Katharina Varnholt, Verena Schroten, Horst Tenenbaum, Tobias Severe Pneumonia and Sepsis Caused by Dialister pneumosintes in an Adolescent |
title | Severe Pneumonia and Sepsis Caused by Dialister pneumosintes in an Adolescent |
title_full | Severe Pneumonia and Sepsis Caused by Dialister pneumosintes in an Adolescent |
title_fullStr | Severe Pneumonia and Sepsis Caused by Dialister pneumosintes in an Adolescent |
title_full_unstemmed | Severe Pneumonia and Sepsis Caused by Dialister pneumosintes in an Adolescent |
title_short | Severe Pneumonia and Sepsis Caused by Dialister pneumosintes in an Adolescent |
title_sort | severe pneumonia and sepsis caused by dialister pneumosintes in an adolescent |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230426/ https://www.ncbi.nlm.nih.gov/pubmed/34200808 http://dx.doi.org/10.3390/pathogens10060733 |
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