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Severe Pneumonia and Sepsis Caused by Dialister pneumosintes in an Adolescent

Background: Dialister pneumosintes (D. pneumosintes) is known to cause dental, periodontal or sinus infections. To date, the pathogen has only been described in a small number of cases with a severe infection. Case report: We describe the clinical case of a 13-year-old, obese female patient that pre...

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Autores principales: Kaiser, Maximilian, Weis, Meike, Kehr, Katharina, Varnholt, Verena, Schroten, Horst, Tenenbaum, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230426/
https://www.ncbi.nlm.nih.gov/pubmed/34200808
http://dx.doi.org/10.3390/pathogens10060733
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author Kaiser, Maximilian
Weis, Meike
Kehr, Katharina
Varnholt, Verena
Schroten, Horst
Tenenbaum, Tobias
author_facet Kaiser, Maximilian
Weis, Meike
Kehr, Katharina
Varnholt, Verena
Schroten, Horst
Tenenbaum, Tobias
author_sort Kaiser, Maximilian
collection PubMed
description Background: Dialister pneumosintes (D. pneumosintes) is known to cause dental, periodontal or sinus infections. To date, the pathogen has only been described in a small number of cases with a severe infection. Case report: We describe the clinical case of a 13-year-old, obese female patient that presented with acute respiratory failure and sepsis. A CT-scan showed extensive bilateral patchy areas, subpleural and peribronchovascular consolidations with surrounding ground-glass opacity, extensive consolidations in the lower lobes of both lungs matching to a severe pneumonia and clinically emerging acute respiratory distress syndrome. Moreover, it showed extensive sinusitis of the right sinus frontalis, maxillaris and right cellulae ethmoidales. D. pneumosintes was isolated from an anaerobic blood culture obtained at admission. The antibiotic treatment included piperacillin/tazobactam and oral switch to ampicillin/sulbactam plus ciprofloxacin. Conclusions: We describe the first adolescent with severe systemic D. pneumosintes infection. Since the pathogen is difficult to culture the systemic virulence remains unclear. This work aims to sensitize health care specialists to consider D. pneumosintes infection in patients with periodontal or sinusal infection.
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spelling pubmed-82304262021-06-26 Severe Pneumonia and Sepsis Caused by Dialister pneumosintes in an Adolescent Kaiser, Maximilian Weis, Meike Kehr, Katharina Varnholt, Verena Schroten, Horst Tenenbaum, Tobias Pathogens Case Report Background: Dialister pneumosintes (D. pneumosintes) is known to cause dental, periodontal or sinus infections. To date, the pathogen has only been described in a small number of cases with a severe infection. Case report: We describe the clinical case of a 13-year-old, obese female patient that presented with acute respiratory failure and sepsis. A CT-scan showed extensive bilateral patchy areas, subpleural and peribronchovascular consolidations with surrounding ground-glass opacity, extensive consolidations in the lower lobes of both lungs matching to a severe pneumonia and clinically emerging acute respiratory distress syndrome. Moreover, it showed extensive sinusitis of the right sinus frontalis, maxillaris and right cellulae ethmoidales. D. pneumosintes was isolated from an anaerobic blood culture obtained at admission. The antibiotic treatment included piperacillin/tazobactam and oral switch to ampicillin/sulbactam plus ciprofloxacin. Conclusions: We describe the first adolescent with severe systemic D. pneumosintes infection. Since the pathogen is difficult to culture the systemic virulence remains unclear. This work aims to sensitize health care specialists to consider D. pneumosintes infection in patients with periodontal or sinusal infection. MDPI 2021-06-10 /pmc/articles/PMC8230426/ /pubmed/34200808 http://dx.doi.org/10.3390/pathogens10060733 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Kaiser, Maximilian
Weis, Meike
Kehr, Katharina
Varnholt, Verena
Schroten, Horst
Tenenbaum, Tobias
Severe Pneumonia and Sepsis Caused by Dialister pneumosintes in an Adolescent
title Severe Pneumonia and Sepsis Caused by Dialister pneumosintes in an Adolescent
title_full Severe Pneumonia and Sepsis Caused by Dialister pneumosintes in an Adolescent
title_fullStr Severe Pneumonia and Sepsis Caused by Dialister pneumosintes in an Adolescent
title_full_unstemmed Severe Pneumonia and Sepsis Caused by Dialister pneumosintes in an Adolescent
title_short Severe Pneumonia and Sepsis Caused by Dialister pneumosintes in an Adolescent
title_sort severe pneumonia and sepsis caused by dialister pneumosintes in an adolescent
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230426/
https://www.ncbi.nlm.nih.gov/pubmed/34200808
http://dx.doi.org/10.3390/pathogens10060733
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