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Analysis of Age-Dependent Alterations in Excitability Properties of CA1 Pyramidal Neurons in an APPPS1 Model of Alzheimer’s Disease

Age-dependent accumulation of amyloid-β, provoking increasing brain amyloidopathy, triggers abnormal patterns of neuron activity and circuit synchronization in Alzheimer’s disease (AD) as observed in human AD patients and AD mouse models. Recent studies on AD mouse models, mimicking this age-depende...

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Detalles Bibliográficos
Autores principales:	Vitale, Paola, Salgueiro-Pereira, Ana Rita, Lupascu, Carmen Alina, Willem, Michael, Migliore, Rosanna, Migliore, Michele, Marie, Hélène
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230571/ https://www.ncbi.nlm.nih.gov/pubmed/34177555 http://dx.doi.org/10.3389/fnagi.2021.668948

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