Augmenting the Immune Response against a Stabilized HIV-1 Clade C Envelope Trimer by Silica Nanoparticle Delivery

The delivery of HIV-1 envelope (Env) trimer-based immunogens on the surface of nanoparticles holds promise to promote immunogenicity with the aim of inducing a potent, durable and broad neutralizing antibody (bnAb) response. Towards that goal, we examined the covalent conjugation of Env to 100 nm an...

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Detalles Bibliográficos
Autores principales: Peterhoff, David, Thalhauser, Stefanie, Sobczak, Jan M., Mohsen, Mona O., Voigt, Christoph, Seifert, Nicole, Neckermann, Patrick, Hauser, Alexandra, Ding, Song, Sattentau, Quentin, Bachmann, Martin F., Breunig, Miriam, Wagner, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230641/
https://www.ncbi.nlm.nih.gov/pubmed/34208059
http://dx.doi.org/10.3390/vaccines9060642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230641/
https://www.ncbi.nlm.nih.gov/pubmed/34208059
http://dx.doi.org/10.3390/vaccines9060642

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