Cargando…

Assessment of Paroxetine Molecular Interactions with Selected Monoamine and γ-Aminobutyric Acid Transporters

Thus far, many hypotheses have been proposed explaining the cause of depression. Among the most popular of these are: monoamine, neurogenesis, neurobiology, inflammation and stress hypotheses. Many studies have proven that neurogenesis in the brains of adult mammals occurs throughout life. The gener...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kowalska, Magdalena, Fijałkowski, Łukasz, Nowaczyk, Alicja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230779/ https://www.ncbi.nlm.nih.gov/pubmed/34208199 http://dx.doi.org/10.3390/ijms22126293

Ejemplares similares

Paroxetine—Overview of the Molecular Mechanisms of Action
por: Kowalska, Magdalena, et al.
Publicado: (2021)

Antiepileptic Drug Tiagabine Does Not Directly Target Key Cardiac Ion Channels Kv11.1, Nav1.5 and Cav1.2
por: Kowalska, Magdalena, et al.
Publicado: (2021)

GATMD: γ-Aminobutyric Acid Transporter Mutagenesis Database
por: Anderson, Cynthia M., et al.
Publicado: (2010)

Acetylsalicylic Acid–Primus Inter Pares in Pharmacology
por: Fijałkowski, Łukasz, et al.
Publicado: (2022)

K(V)11.1, Na(V)1.5, and Ca(V)1.2 Transporter Proteins as Antitarget for Drug Cardiotoxicity
por: Kowalska, Magdalena, et al.
Publicado: (2020)

Expression and functions of glutamate and γ-aminobutyric acid transporters in ischemic models
por: Qian, Zhongrun, et al.
Publicado: (2018)

A half century of γ-aminobutyric acid
por: Smart, Trevor G, et al.
Publicado: (2019)

Beyond the γ-aminobutyric acid hypothesis of schizophrenia
por: Fujihara, Kazuyuki
Publicado: (2023)

Probing the Selectivity of Monoamine Transporter Substrates by Means of Molecular Modeling
por: Seddik, Amir, et al.
Publicado: (2013)

Role of the conserved glutamine 291 in the rat γ-aminobutyric acid transporter rGAT-1
por: Mari, S. A., et al.
Publicado: (2005)

Impact of Dysfunctional Feed-Forward Inhibition on Glutamate Decarboxylase Isoforms and γ-Aminobutyric Acid Transporters
por: Panthi, Sandesh, et al.
Publicado: (2021)

An Overview of Bioprocesses Employing Specifically Selected Microbial Catalysts for γ-Aminobutyric Acid Production
por: Dahiya, Divakar, et al.
Publicado: (2021)

An Intermediate State of the γ-Aminobutyric Acid Transporter Gat1 Revealed by Simultaneous Voltage Clamp and Fluorescence
por: Li, Ming, et al.
Publicado: (2000)

γ-Aminobutyric Acid Transporter 2 Mediates the Hepatic Uptake of Guanidinoacetate, the Creatine Biosynthetic Precursor, in Rats
por: Tachikawa, Masanori, et al.
Publicado: (2012)

Picrotoxin Delineates Different Transport Configurations for Malate and γ Aminobutyric Acid through TaALMT1
por: Ramesh, Sunita A., et al.
Publicado: (2022)

Production of gaba (γ – Aminobutyric acid) by microorganisms: a review
por: Dhakal, Radhika, et al.
Publicado: (2012)

Visual cortical γ−aminobutyric acid and perceptual suppression in amblyopia
por: Mukerji, Arjun, et al.
Publicado: (2022)

Mechanism of Paroxetine (Paxil) Inhibition of the Serotonin Transporter
por: Davis, Bruce A., et al.
Publicado: (2016)

Interaction between γ-Aminobutyric Acid A Receptor Genes: New Evidence in Migraine Susceptibility
por: Quintas, Marlene, et al.
Publicado: (2013)

GRID-independent molecular descriptor analysis and molecular docking studies to mimic the binding hypothesis of γ-aminobutyric acid transporter 1 (GAT1) inhibitors
por: Zafar, Sadia, et al.
Publicado: (2019)

Concatenated γ-aminobutyric acid type A receptors revisited: Finding order in chaos
por: Liao, Vivian Wan Yu, et al.
Publicado: (2019)

Development of a workflow for the selection, identification and optimization of lactic acid bacteria with high γ-aminobutyric acid production
por: Rehman, Ateequr, et al.
Publicado: (2023)

Carbon Monoxide and Nitric Oxide as Examples of the Youngest Class of Transmitters
por: Nowaczyk, Alicja, et al.
Publicado: (2021)

Waggle needling wields preferable neuroprotective and anti-spastic effects on post-stroke spasticity rats by attenuating γ-aminobutyric acid transaminase and enhancing γ-aminobutyric acid.
por: Wang, Jun-Xiang, et al.
Publicado: (2020)

γ-Aminobutyric Acid Suppresses Iron Transportation from Roots to Shoots in Rice Seedlings by Inducing Aerenchyma Formation
por: Zhu, Changhua, et al.
Publicado: (2020)

γ-Aminobutyric acid (GABA) administration improves action selection processes: a randomised controlled trial
por: Steenbergen, Laura, et al.
Publicado: (2015)

Suppression of Progesterone-enhanced Hyperactivation in Hamster Spermatozoa by γ-aminobutyric Acid
por: KON, Hiroe, et al.
Publicado: (2014)

Synaptic inhibition and γ-aminobutyric acid in the mammalian central nervous system
por: OBATA, Kunihiko
Publicado: (2013)

Acidification and γ-aminobutyric acid independently alter kairomone-induced behaviour
por: Charpentier, Corie L., et al.
Publicado: (2016)

Effect of γ-Aminobutyric Acid–Chitosan Nanoparticles on Glucose Homeostasis in Mice
por: Liu, Yuangang, et al.
Publicado: (2018)

Anterior cingulate cortex γ-aminobutyric acid deficits in youth with depression
por: Gabbay, V, et al.
Publicado: (2017)

Motor inhibition efficiency in healthy aging: the role of γ-aminobutyric acid
por: Pauwels, Lisa, et al.
Publicado: (2019)

γ-Aminobutyric acid found in fermented foods and beverages: current trends
por: Sahab, Novia R.M., et al.
Publicado: (2020)

Functional Characterization of the γ-Aminobutyric Acid Transporter from Mycobacterium smegmatis MC(2) 155 Reveals Sodium-Driven GABA Transport
por: Pavić, Ana, et al.
Publicado: (2021)

Substrate Selectivity of the Acid-activated Glutamate/γ-Aminobutyric acid (GABA) Antiporter GadC from Escherichia coli
por: Ma, Dan, et al.
Publicado: (2013)

Monoamine transporters: insights from molecular dynamics simulations
por: Grouleff, Julie, et al.
Publicado: (2015)

Functional Consequences of Sulfhydryl Modification of the γ-Aminobutyric Acid Transporter 1 at a Single Solvent-Exposed Cysteine Residue
por: Omoto, Jaison J., et al.
Publicado: (2012)

A Binding Mode Hypothesis of Tiagabine Confirms Liothyronine Effect on γ-Aminobutyric Acid Transporter 1 (GAT1)
por: Jurik, Andreas, et al.
Publicado: (2015)

Structure, Function, and Modulation of γ-Aminobutyric Acid Transporter 1 (GAT1) in Neurological Disorders: A Pharmacoinformatic Prospective
por: Zafar, Sadia, et al.
Publicado: (2018)

A Novel Gene Coding γ-Aminobutyric Acid Transporter May Improve the Tolerance of Populus euphratica to Adverse Environments
por: Bai, Xiaotao, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_elqoblh455f98oh160bf8iu0s3